Publications

178. Rosa-Bauza, Y. T.; Berst, F.; Ellman, J. A.
Straightforward Preparation and Assay of Aspartyl Protease Substrates with an Internal Thioester Linkage
ChemBioChem  2007, 8, 981-984.
177. Ellman, J. A
The Direct Approach
Science  2007, 316, 1131-1132.
176. Inagaki, H.; Tsuruoka, H.; Hornsby, M.; Lesley, S. A.; Spraggon, G.; Ellman, J. A.
Nonpeptidic Inhibitors of Cathepsin S with an Unprecedented Binding Mode
J. Med. Chem.  2007, 50, 2693-2699.
175. Lewis, J. C.; Bergman, R. G.; Ellman, J. A.
Rh(I)-Catalyzed Alkylation of Quinolines and Pyridines via C-H Bond Activation
J. Am. Chem. Soc.  2007, 129, 5332-5333.
Write-up in Organic Process Research and Development
174. Rech, J. C.; Yato, M.; Duckett, D.; Ember, Brian; LoGrasso, P. V.; Bergman, R. G.; Ellman, J. A.
Synthesis of Potent Bicyclic Bisarylimidazole c-Jun N-Terminal Kinase Inhibitors by Catalytic C-H Bond Activation
J. Am. Chem. Soc.  2007, 129, 490-491.
173. Tanuwidjaja, J.; Peltier, H. M.; Ellman, J. A
One-Pot Asymmetric Synthesis of Either Diastereomer of tert-Butanesulfinyl-protected Amines from Ketones
J. Org. Chem.  2007, 72, 626-629.
172. Liu, G. L.; Rosa-Bauza, Y. T.; Salisbury, C. T.; Lu, Y.; Kim, J.; Craik, C.; Ellman, J. A.; Lee, L. P.; Chen, F. F.
Peptide-Nanocrescent Hybrid SERS Probe for Optical Detection of Protease Activity
J. Nanoscience Nanotech.  2007, 7, 2323–2330.
171. Peltier, H. M.; McMahon, J. P.; Patterson, A. W.; Ellman, J. A.
The Total Synthesis of Tubulysin D
J. Am. Chem. Soc.   2006, 128, 16018-16019.
170. Patterson, A. W.; Wood, W. J. L.; Ellman, J. A.
Substrate Activity Acreening (SAS): a General Procedure for the Preparation and Screening of a Fragment-Based Non-Peptidic Protease Substrate Library for Inhibitor Discovery
Nat. Protoc.  2007, 2, 424 - 433.
169. Patterson, A. W.; Wood, W. J. L.; Hornsby, M.; Lesley, S.; Spraggon, G.; Ellman, J. A.
Identification of Selective, Nonpeptidic Nitrile Inhibitors of Cathepsin S using the Substrate Activity Screening Method
J. Med. Chem.  2006, 49, 6298-6307.
168. Watzke, A.; O’Malley, S. J.; Bergman, R. G.; Ellman, J. A.
Reassignment of Configuration for Salvianolic Acid B and Establishment of Its Identity with Lithospermic Acid B
J. Nat. Prod.  2006, 69, 1231-1233.
167. Patterson, A. W.; Ellman, J. A.
Asymmetric Synthesis of alpha,alpha-Dibranched Propargylamines by Acetylide Additions to N-tert-Butanesulfinyl Ketimines
J. Org. Chem.  2006, 71,  7110-7112.
166. Salisbury , C. M.; Ellman, J. A.
Rapid Identification of Potent Nonpeptidic Serine Protease Inhibitors
ChemBioChem  2006, 7, 1034-1037.
165. Zhang, Y.; Lewis, J. C.; Bergman, R. G.; Ellman, J. A.; Oldfield, E.
NMR Shifts, Orbitals, and M···H-X Bonding in d8 Square Planar Metal Complexes
Organometallics   2006, 25, 3515-3519.
164. Choe, Y.; Leonetti, F.; Greenbaum, D. C.; Lecaille, F.; Bogyo, M.; Bromme, D.; Ellman, J. A.; Craik, C. S.
Substrate Profiling of Cysteine Proteases Using a Combinatorial Peptide Library Identifies Functionally Unique Specificities
J. Biol. Chem.  2006, 281, 12824-12832.
163. Gosalia D.N.; Denney, W. S.; Salisbury, C. M.; Ellman, J. A.; Diamond, S. L.
Functional Phenotyping of Human Plasma Using a 361-Fluorogenic Substrate Biosensing Microarray
Biotechnol. Bioeng.  2006, 94, 1099-1110.
162. Wilson, R. M.; Thalji, R. K.; Bergman, R. G.; Ellman, J. A.
Enantioselective Synthesis of a PKC Inhibitor via Catalytic C-H Bond Activation
Org. Lett.  2006, 8, 1745-1747.
161. Beenen, M. A.; Weix, D. J.; Ellman, J. A.
Asymmetric Synthesis of Protected Arylglycines by Rhodium-Catalyzed Addition of Arylboronic Acids to N-tert-Butanesulfinyl Imino Esters
J. Am. Chem. Soc.  2006, 128, 6304-6305.
Write-up in Organic Process Research and Development
160. Colby, D. A.; Bergman, R. G.; Ellman, J. A.
Stereoselective Alkylation of alpha,beta-Unsaturated Imines via C-H Bond Activation
J. Am. Chem. Soc.  2006, 128,  5604-05.
159. Lewis, J. C.; Wu, J. Y.; Ellman, J. A.; Bergman, R. G.
Microwave-Promoted Rhodium-Catalyzed Arylation of Heterocycles through CH Bond Activation
Angew. Chem. Int. Ed.  2006, 45, 1589-1591.
158. Wiedemann, S. H.; Lewis, J. C.; Ellman, J. A.; Bergman, R. G.
Experimental and Computational Studies on the Mechanism of N-Heterocycle C-H Activation by Rh(I)
J. Am. Chem. Soc.   2006, 128, 2452-2462.
157. Wiedemann, S. H.; Ellman, J. A.; Bergman, R. G.
Rhodium-Catalyzed Direct C-H Addition of 3,4-Dihydroquinazolines to Alkenes and Their Use in the Total Synthesis of Vasicoline
J. Org. Chem.  2006, 71, 1969-1976.
Write-up in Organic Process Research and Development
156. Wood, W. J. L.; Patterson, A. W.; Tsuruoka, H.; Jain, R. K.; Ellman, J. A
Substrate Activity Screening: A Fragment-Based Method for the Rapid Identification of Nonpeptidic Protease Inhibitors
J. Am. Chem. Soc.  2005, 127, 5521-15527.
Research Highlight in Nature Chemical Biology
155. McMahon, J. P.; Ellman, J. A.
Asymmetric Conjugate Addition of Copper Reagents to alpha,beta-Unsaturated tert-Butanesulfinyl Imines
Org. Lett.  2005, 7, 5393-5396.
154. Weix, D. J.; Ellman, J. A.
(+)-2-Methyl-2-propanesulfinamide
Org. Synth.  2005, 82, 157-165.
153. Lewis, J. C.; Wu, J.; Bergman, R. G.; Ellman, J. A.
Preagostic Rh-H Interactions and C-H Bond Functionalization: A Combined Experimental and Theoretical Investigation of Rhodium(I) Phosphinite Complexes
Organometallics  2005, 24, 5737-5746.
152. O'Malley, S. J.; Tan, K. L.; Watzke, A.; Bergman, R. G.; Ellman, J. A.
Total Synthesis of (+)-Lithospermic Acid by Asymmetric Intramolecular Alkylation via Catalytic C-H Bond Activation
J. Am. Chem. Soc  2005, 127, 13496-13497.
151. Peltier, H. M.; Ellman, J. A.
N-Sulfinyl Metalloenamine Conjugate Additions: Asymmetric Synthesis of Piperidines
J. Org. Chem.  2005, 70, 7342-7345.
150. Thalji, R. K.; Ahrendt, K. A.; Bergman, R. G.; Ellman, J. A.
Annulation of Aromatic Imines via Directed C-H Bond Activation
J. Org. Chem.  2005, 70, 6775-6781.
149. Brinner, K. M.; Ellman, J. A.
A Rapid and General Method for the Asymmetric Synthesis of 2-Substituted Pyrrolidines Using tert-Butanesulfinamide
Org. Biomol. Chem.  2005, 3, 2109-2113.

Pages