Publications
170. |
Patterson, A. W.; Wood, W. J. L.; Ellman, J. A. Substrate Activity Acreening (SAS): a General Procedure for the Preparation and Screening of a Fragment-Based Non-Peptidic Protease Substrate Library for Inhibitor Discovery Nat. Protoc. 2007, 2, 424 - 433. |
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169. |
Patterson, A. W.; Wood, W. J. L.; Hornsby, M.; Lesley, S.; Spraggon, G.; Ellman, J. A. Identification of Selective, Nonpeptidic Nitrile Inhibitors of Cathepsin S using the Substrate Activity Screening Method J. Med. Chem. 2006, 49, 6298-6307. |
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168. |
Watzke, A.; O’Malley, S. J.; Bergman, R. G.; Ellman, J. A. Reassignment of Configuration for Salvianolic Acid B and Establishment of Its Identity with Lithospermic Acid B J. Nat. Prod. 2006, 69, 1231-1233. |
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167. |
Patterson, A. W.; Ellman, J. A. Asymmetric Synthesis of alpha,alpha-Dibranched Propargylamines by Acetylide Additions to N-tert-Butanesulfinyl Ketimines J. Org. Chem. 2006, 71, 7110-7112. |
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166. |
Salisbury , C. M.; Ellman, J. A. Rapid Identification of Potent Nonpeptidic Serine Protease Inhibitors ChemBioChem 2006, 7, 1034-1037. |
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165. |
Zhang, Y.; Lewis, J. C.; Bergman, R. G.; Ellman, J. A.; Oldfield, E. NMR Shifts, Orbitals, and M···H-X Bonding in d8 Square Planar Metal Complexes Organometallics 2006, 25, 3515-3519. |
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164. |
Choe, Y.; Leonetti, F.; Greenbaum, D. C.; Lecaille, F.; Bogyo, M.; Bromme, D.; Ellman, J. A.; Craik, C. S. Substrate Profiling of Cysteine Proteases Using a Combinatorial Peptide Library Identifies Functionally Unique Specificities J. Biol. Chem. 2006, 281, 12824-12832. |
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163. |
Gosalia D.N.; Denney, W. S.; Salisbury, C. M.; Ellman, J. A.; Diamond, S. L. Functional Phenotyping of Human Plasma Using a 361-Fluorogenic Substrate Biosensing Microarray Biotechnol. Bioeng. 2006, 94, 1099-1110. |
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162. |
Wilson, R. M.; Thalji, R. K.; Bergman, R. G.; Ellman, J. A. Enantioselective Synthesis of a PKC Inhibitor via Catalytic C-H Bond Activation Org. Lett. 2006, 8, 1745-1747. |
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161. |
Beenen, M. A.; Weix, D. J.; Ellman, J. A. Asymmetric Synthesis of Protected Arylglycines by Rhodium-Catalyzed Addition of Arylboronic Acids to N-tert-Butanesulfinyl Imino Esters J. Am. Chem. Soc. 2006, 128, 6304-6305. Write-up in Organic Process Research and Development |
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160. |
Colby, D. A.; Bergman, R. G.; Ellman, J. A. Stereoselective Alkylation of alpha,beta-Unsaturated Imines via C-H Bond Activation J. Am. Chem. Soc. 2006, 128, 5604-05. |
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159. |
Lewis, J. C.; Wu, J. Y.; Ellman, J. A.; Bergman, R. G. Microwave-Promoted Rhodium-Catalyzed Arylation of Heterocycles through CH Bond Activation Angew. Chem. Int. Ed. 2006, 45, 1589-1591. |
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158. |
Wiedemann, S. H.; Lewis, J. C.; Ellman, J. A.; Bergman, R. G. Experimental and Computational Studies on the Mechanism of N-Heterocycle C-H Activation by Rh(I) J. Am. Chem. Soc. 2006, 128, 2452-2462. |
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157. |
Wiedemann, S. H.; Ellman, J. A.; Bergman, R. G. Rhodium-Catalyzed Direct C-H Addition of 3,4-Dihydroquinazolines to Alkenes and Their Use in the Total Synthesis of Vasicoline J. Org. Chem. 2006, 71, 1969-1976. Write-up in Organic Process Research and Development |
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156. |
Wood, W. J. L.; Patterson, A. W.; Tsuruoka, H.; Jain, R. K.; Ellman, J. A Substrate Activity Screening: A Fragment-Based Method for the Rapid Identification of Nonpeptidic Protease Inhibitors J. Am. Chem. Soc. 2005, 127, 5521-15527. Research Highlight in Nature Chemical Biology |
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155. |
McMahon, J. P.; Ellman, J. A. Asymmetric Conjugate Addition of Copper Reagents to alpha,beta-Unsaturated tert-Butanesulfinyl Imines Org. Lett. 2005, 7, 5393-5396. |
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154. |
Weix, D. J.; Ellman, J. A. (+)-2-Methyl-2-propanesulfinamide Org. Synth. 2005, 82, 157-165. |
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153. |
Lewis, J. C.; Wu, J.; Bergman, R. G.; Ellman, J. A. Preagostic Rh-H Interactions and C-H Bond Functionalization: A Combined Experimental and Theoretical Investigation of Rhodium(I) Phosphinite Complexes Organometallics 2005, 24, 5737-5746. |
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152. |
O'Malley, S. J.; Tan, K. L.; Watzke, A.; Bergman, R. G.; Ellman, J. A. Total Synthesis of (+)-Lithospermic Acid by Asymmetric Intramolecular Alkylation via Catalytic C-H Bond Activation J. Am. Chem. Soc 2005, 127, 13496-13497. |
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151. |
Peltier, H. M.; Ellman, J. A. N-Sulfinyl Metalloenamine Conjugate Additions: Asymmetric Synthesis of Piperidines J. Org. Chem. 2005, 70, 7342-7345. |
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150. |
Thalji, R. K.; Ahrendt, K. A.; Bergman, R. G.; Ellman, J. A. Annulation of Aromatic Imines via Directed C-H Bond Activation J. Org. Chem. 2005, 70, 6775-6781. |
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149. |
Brinner, K. M.; Ellman, J. A. A Rapid and General Method for the Asymmetric Synthesis of 2-Substituted Pyrrolidines Using tert-Butanesulfinamide Org. Biomol. Chem. 2005, 3, 2109-2113. |
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148. |
Ghosalia, D. N.; Salisbury, C. M.; Maly, D. J.; Ellman, J. A.; Diamond, S. L. Profiling Serine Protease Substrate Specificity with Solution Phase Fluorogenic Peptide Microarrays Proteomics 2005, 5, 1292-1298. |
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147. |
Wiedemann, S. H.; Ellman, J. A.; Bergman, R. G. Catalytic Functionalization of N-Heterocycles via their Rhodium-Carbene Complexes. In Handbook of C-H Transformations; Dyker, G., Ed.: Wiley-VCH Verlag GmbH & Co. KGaA; Weinheim, 2005, , 187-193. |
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146. |
Gosalia, D. N.; Salisbury, C. M.; Ellman, J. A.; Diamond, S. L. High Throughput Substrate Specificity Profiling of Serine and Cysteine Proteases Using Solution-Phase Fluorogenic Peptide Microarays Molec. Cell. Proteomics 2005, 4, 626-636. |
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145. |
Peltier, H. M.; Evans, J. W.; Ellman, J. A. Catalytic Enantioselective Sulfinyl Transfer Using Cinchona Alkaloid Catalysts Org. Lett. 2005, 7, 1733-1736. |
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144. |
Brinner, K.; Ellman, J. A. “Asymmetric Synthesis of ß-Amino Acids by Enolate Additions to tert-Butanesulfinyl Imines” In Enantioselective Synthesis of ß-Amino Acids, 2nd Edition; Juaristi, E., Soloshonok, V., Eds.; John Wiley & Sons, Hoboken, NJ; 2005, , 181-194. |
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143. |
Brinner, K. M.; Powles, M. A.; Schmatz, D. M.; Ellman, J. A. Potent 4-Aminopiperidine Based Antimalarial Agents Bioorg. Med. Chem. Lett. 2005, 15, 345-348. |
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142. |
Weix, D. J.; Shi, Y.; Ellman, J. A. Diastereoselective and Enantioselective Rh(I)-Catalyzed Additions of Arylboronic Acids to N-tert-Butanesulfinyl and N-Diphenylphosphinoyl Aldimines J. Am. Chem. Soc. 2005, 127, 1092-1093. |
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141. |
Kochi , T.; Ellman, J. A. Asymmetric alpha-Alkylation of N’-tert-Butanesulfinyl Amidines. Application to the Total Synthesis of (6R,7S)-7-Amino-7,8-dihydro-alpha-bisabolene J. Am. Chem. Soc. 2004, 126, 15652-15653. |