Publications

170. Patterson, A. W.; Wood, W. J. L.; Ellman, J. A.
Substrate Activity Acreening (SAS): a General Procedure for the Preparation and Screening of a Fragment-Based Non-Peptidic Protease Substrate Library for Inhibitor Discovery
Nat. Protoc.  20072, 424 - 433.
169. Patterson, A. W.; Wood, W. J. L.; Hornsby, M.; Lesley, S.; Spraggon, G.; Ellman, J. A.
Identification of Selective, Nonpeptidic Nitrile Inhibitors of Cathepsin S using the Substrate Activity Screening Method
J. Med. Chem.  200649, 6298-6307.
168. Watzke, A.; O’Malley, S. J.; Bergman, R. G.; Ellman, J. A.
Reassignment of Configuration for Salvianolic Acid B and Establishment of Its Identity with Lithospermic Acid B
J. Nat. Prod.  200669, 1231-1233.
167. Patterson, A. W.; Ellman, J. A.
Asymmetric Synthesis of alpha,alpha-Dibranched Propargylamines by Acetylide Additions to N-tert-Butanesulfinyl Ketimines
J. Org. Chem.  200671,  7110-7112.
166. Salisbury , C. M.; Ellman, J. A.
Rapid Identification of Potent Nonpeptidic Serine Protease Inhibitors
ChemBioChem  20067, 1034-1037.
165. Zhang, Y.; Lewis, J. C.; Bergman, R. G.; Ellman, J. A.; Oldfield, E.
NMR Shifts, Orbitals, and M···H-X Bonding in d8 Square Planar Metal Complexes
Organometallics   200625, 3515-3519.
164. Choe, Y.; Leonetti, F.; Greenbaum, D. C.; Lecaille, F.; Bogyo, M.; Bromme, D.; Ellman, J. A.; Craik, C. S.
Substrate Profiling of Cysteine Proteases Using a Combinatorial Peptide Library Identifies Functionally Unique Specificities
J. Biol. Chem.  2006281, 12824-12832.
163. Gosalia D.N.; Denney, W. S.; Salisbury, C. M.; Ellman, J. A.; Diamond, S. L.
Functional Phenotyping of Human Plasma Using a 361-Fluorogenic Substrate Biosensing Microarray
Biotechnol. Bioeng.  200694, 1099-1110.
162. Wilson, R. M.; Thalji, R. K.; Bergman, R. G.; Ellman, J. A.
Enantioselective Synthesis of a PKC Inhibitor via Catalytic C-H Bond Activation
Org. Lett.  20068, 1745-1747.
161. Beenen, M. A.; Weix, D. J.; Ellman, J. A.
Asymmetric Synthesis of Protected Arylglycines by Rhodium-Catalyzed Addition of Arylboronic Acids to N-tert-Butanesulfinyl Imino Esters
J. Am. Chem. Soc.  2006128, 6304-6305.
Write-up in Organic Process Research and Development
160. Colby, D. A.; Bergman, R. G.; Ellman, J. A.
Stereoselective Alkylation of alpha,beta-Unsaturated Imines via C-H Bond Activation
J. Am. Chem. Soc.  2006128,  5604-05.
159. Lewis, J. C.; Wu, J. Y.; Ellman, J. A.; Bergman, R. G.
Microwave-Promoted Rhodium-Catalyzed Arylation of Heterocycles through CH Bond Activation
Angew. Chem. Int. Ed.  200645, 1589-1591.
158. Wiedemann, S. H.; Lewis, J. C.; Ellman, J. A.; Bergman, R. G.
Experimental and Computational Studies on the Mechanism of N-Heterocycle C-H Activation by Rh(I)
J. Am. Chem. Soc.   2006128, 2452-2462.
157. Wiedemann, S. H.; Ellman, J. A.; Bergman, R. G.
Rhodium-Catalyzed Direct C-H Addition of 3,4-Dihydroquinazolines to Alkenes and Their Use in the Total Synthesis of Vasicoline
J. Org. Chem.  200671, 1969-1976.
Write-up in Organic Process Research and Development
156. Wood, W. J. L.; Patterson, A. W.; Tsuruoka, H.; Jain, R. K.; Ellman, J. A
Substrate Activity Screening: A Fragment-Based Method for the Rapid Identification of Nonpeptidic Protease Inhibitors
J. Am. Chem. Soc.  2005127, 5521-15527.
Research Highlight in Nature Chemical Biology
155. McMahon, J. P.; Ellman, J. A.
Asymmetric Conjugate Addition of Copper Reagents to alpha,beta-Unsaturated tert-Butanesulfinyl Imines
Org. Lett.  20057, 5393-5396.
154. Weix, D. J.; Ellman, J. A.
(+)-2-Methyl-2-propanesulfinamide
Org. Synth.  200582, 157-165.
153. Lewis, J. C.; Wu, J.; Bergman, R. G.; Ellman, J. A.
Preagostic Rh-H Interactions and C-H Bond Functionalization: A Combined Experimental and Theoretical Investigation of Rhodium(I) Phosphinite Complexes
Organometallics  200524, 5737-5746.
152. O'Malley, S. J.; Tan, K. L.; Watzke, A.; Bergman, R. G.; Ellman, J. A.
Total Synthesis of (+)-Lithospermic Acid by Asymmetric Intramolecular Alkylation via Catalytic C-H Bond Activation
J. Am. Chem. Soc  2005127, 13496-13497.
151. Peltier, H. M.; Ellman, J. A.
N-Sulfinyl Metalloenamine Conjugate Additions: Asymmetric Synthesis of Piperidines
J. Org. Chem.  200570, 7342-7345.
150. Thalji, R. K.; Ahrendt, K. A.; Bergman, R. G.; Ellman, J. A.
Annulation of Aromatic Imines via Directed C-H Bond Activation
J. Org. Chem.  200570, 6775-6781.
149. Brinner, K. M.; Ellman, J. A.
A Rapid and General Method for the Asymmetric Synthesis of 2-Substituted Pyrrolidines Using tert-Butanesulfinamide
Org. Biomol. Chem.  20053, 2109-2113.
148. Ghosalia, D. N.; Salisbury, C. M.; Maly, D. J.; Ellman, J. A.; Diamond, S. L.
Profiling Serine Protease Substrate Specificity with Solution Phase Fluorogenic Peptide Microarrays
Proteomics  20055, 1292-1298.
147. Wiedemann, S. H.; Ellman, J. A.; Bergman, R. G.
Catalytic Functionalization of N-Heterocycles via their Rhodium-Carbene Complexes.
In Handbook of C-H Transformations; Dyker, G., Ed.: Wiley-VCH Verlag GmbH & Co. KGaA; Weinheim,  2005, 187-193.
146. Gosalia, D. N.; Salisbury, C. M.; Ellman, J. A.; Diamond, S. L.
High Throughput Substrate Specificity Profiling of Serine and Cysteine Proteases Using Solution-Phase Fluorogenic Peptide Microarays
Molec. Cell. Proteomics  20054, 626-636.
145. Peltier, H. M.; Evans, J. W.; Ellman, J. A.
Catalytic Enantioselective Sulfinyl Transfer Using Cinchona Alkaloid Catalysts
Org. Lett.  20057, 1733-1736.
144. Brinner, K.; Ellman, J. A.
“Asymmetric Synthesis of  ß-Amino Acids by Enolate Additions to tert-Butanesulfinyl Imines” In Enantioselective  Synthesis of ß-Amino Acids, 2nd Edition; Juaristi, E., Soloshonok, V.,  Eds.; John Wiley & Sons, Hoboken, NJ;
  2005, 181-194.
143. Brinner, K. M.; Powles, M. A.; Schmatz, D. M.; Ellman, J. A.
Potent 4-Aminopiperidine Based Antimalarial Agents
Bioorg. Med. Chem. Lett.  200515, 345-348.
142. Weix, D. J.; Shi, Y.; Ellman, J. A.
Diastereoselective and Enantioselective Rh(I)-Catalyzed Additions of Arylboronic Acids to N-tert-Butanesulfinyl and N-Diphenylphosphinoyl Aldimines
J. Am. Chem. Soc.  2005127, 1092-1093.
141. Kochi , T.; Ellman, J. A.
Asymmetric alpha-Alkylation of N’-tert-Butanesulfinyl Amidines. Application to the Total Synthesis of (6R,7S)-7-Amino-7,8-dihydro-alpha-bisabolene
J. Am. Chem. Soc.  2004126, 15652-15653.

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