Publications

192. Beenen, M. A.; An, C.; Ellman, J. A.
Asymmetric Copper-Catalyzed Synthesis of alpha-Amino Boronate Esters from N-tert-Butanesulfinyl Aldimines
J. Am. Chem. Soc.   2008, 130, 6910-6911.
191. Patterson, A. W.; Peltier, H. M.; Ellman, J. A.
Expedient Synthesis of N-Methyl Tubulysin Analogues with High Cytotoxicity
J. Org. Chem.   2008, 73, 4362-4369.
190. Gribble, M. W.; Ellman, J. A.; Bergman, R. G.
Synthesis of a Benzodiazepine-Derived Rhodium NHC Complex by C-H Bond Activation
Organometallics  2008, 27, 2152-2155.
189. Brak, K.; Doyle, P. S.; McKerrow, J. H.; Ellman, J. A.
Identification of a New Class of Nonpeptidic Inhibitors of Cruzain
J. Am. Chem. Soc.  2008, 130, 6404-6410.
188. Tsai, A. S.; Bergman, R. G.; Ellman, J. A.
Asymmetric Synthesis of (−)-Incarvillateine Employing an Intramolecular Alkylation via Rh-Catalyzed Olefinic C−H Bond Activation
J. Am. Chem. Soc.  2008, 130, 6316-6317.
187. Colby, D. A.; Bergman, R. G.; Ellman, J. A.
Synthesis of Dihydropyridines and Pyridines from Imines and Alkynes via C-H Activation
J. Am. Chem. Soc.  2008, 130, 3645-3651.
186. Yotphan, S.; Bergman, R. G.; Ellman, J. A.
The Stereoselective Formation of Bicyclic Enamines with Bridgehead Unsaturation via Tandem C-H Bond Activation/Alkenylation/Electrocyclization
J. Am. Chem. Soc.   2008, 130, 2452-2453.
185. Lewis, J. C.; Berman, A. M.; Bergman, R. G.; Ellman, J. A.
Rh(I)-Catalyzed Arylation of Heterocycles via C-H Bond Activation:  Expanded Scope Through Mechanistic Insight.
J. Am. Chem. Soc.  2008, 130, 2493-2500.
184. Robak, M. T.; Trincado, M.; Ellman, J. A.
Enantioselective Aza-Henry Reaction with an N-Sulfinyl Urea Organocatalyst
J. Am. Chem. Soc.  2007, 129, 15110-15111.
183. Nakagawa, H.; Rech, J. C.; Sindelar, R. W.; Ellman, J. A.
Catalytic Enantioselective Addition of Arylboronic Acids to N-Boc Imines Generated in Situ
Org. Lett.  2007, 9, 5155-5157.
Write-up in Organic Process Research and Development
182. Patterson, A. W.; Peltier, H. M.; Sasse, F.; Ellman, J. A.
Design, Synthesis, and Biological Properties of Highly Potent Tubulysin D Analogues
Chem. Eur. J.   2007, 13, 9534-9541.
181. Tanuwidjaja, J.; Peltier, H. M.; Lewis, J. C.; Schenkel, L. B.; Ellman, J. A.
One-Pot Microwave-Promoted Synthesis of Nitriles from Aldehydes via tert-Butanesulfinyl Imines
Synthesis   2007, , 3385-3389.
180. Watzke, A.; Wilson, R. M.; O’Malley, S. J.; Bergman, R. G.; Ellman, J. A.
Asymmetric Intramolecular Alkylation of Chiral Aromatic Imines via Catalytic C-H Bond Activation
Synlett   2007, , 2383-2389.
179. Soellner, M. B.; Rawles, K. A.; Grundner, C.; Alber, T.; Ellman, J. A.
Fragment-Based Substrate Activity Screening Method for the Identification of Potent Inhibitors of the M. tuberculosis Phosphatase PtpB
J. Am. Chem. Soc.  2007, 129, 9613-9615.
Research Highlight in Nature Chemical Biology
178. Rosa-Bauza, Y. T.; Berst, F.; Ellman, J. A.
Straightforward Preparation and Assay of Aspartyl Protease Substrates with an Internal Thioester Linkage
ChemBioChem  2007, 8, 981-984.
177. Ellman, J. A
The Direct Approach
Science  2007, 316, 1131-1132.
176. Inagaki, H.; Tsuruoka, H.; Hornsby, M.; Lesley, S. A.; Spraggon, G.; Ellman, J. A.
Nonpeptidic Inhibitors of Cathepsin S with an Unprecedented Binding Mode
J. Med. Chem.  2007, 50, 2693-2699.
175. Lewis, J. C.; Bergman, R. G.; Ellman, J. A.
Rh(I)-Catalyzed Alkylation of Quinolines and Pyridines via C-H Bond Activation
J. Am. Chem. Soc.  2007, 129, 5332-5333.
Write-up in Organic Process Research and Development
174. Rech, J. C.; Yato, M.; Duckett, D.; Ember, Brian; LoGrasso, P. V.; Bergman, R. G.; Ellman, J. A.
Synthesis of Potent Bicyclic Bisarylimidazole c-Jun N-Terminal Kinase Inhibitors by Catalytic C-H Bond Activation
J. Am. Chem. Soc.  2007, 129, 490-491.
173. Tanuwidjaja, J.; Peltier, H. M.; Ellman, J. A
One-Pot Asymmetric Synthesis of Either Diastereomer of tert-Butanesulfinyl-protected Amines from Ketones
J. Org. Chem.  2007, 72, 626-629.
172. Liu, G. L.; Rosa-Bauza, Y. T.; Salisbury, C. T.; Lu, Y.; Kim, J.; Craik, C.; Ellman, J. A.; Lee, L. P.; Chen, F. F.
Peptide-Nanocrescent Hybrid SERS Probe for Optical Detection of Protease Activity
J. Nanoscience Nanotech.  2007, 7, 2323–2330.
171. Peltier, H. M.; McMahon, J. P.; Patterson, A. W.; Ellman, J. A.
The Total Synthesis of Tubulysin D
J. Am. Chem. Soc.   2006, 128, 16018-16019.
170. Patterson, A. W.; Wood, W. J. L.; Ellman, J. A.
Substrate Activity Acreening (SAS): a General Procedure for the Preparation and Screening of a Fragment-Based Non-Peptidic Protease Substrate Library for Inhibitor Discovery
Nat. Protoc.  2007, 2, 424 - 433.
169. Patterson, A. W.; Wood, W. J. L.; Hornsby, M.; Lesley, S.; Spraggon, G.; Ellman, J. A.
Identification of Selective, Nonpeptidic Nitrile Inhibitors of Cathepsin S using the Substrate Activity Screening Method
J. Med. Chem.  2006, 49, 6298-6307.
168. Watzke, A.; O’Malley, S. J.; Bergman, R. G.; Ellman, J. A.
Reassignment of Configuration for Salvianolic Acid B and Establishment of Its Identity with Lithospermic Acid B
J. Nat. Prod.  2006, 69, 1231-1233.
167. Patterson, A. W.; Ellman, J. A.
Asymmetric Synthesis of alpha,alpha-Dibranched Propargylamines by Acetylide Additions to N-tert-Butanesulfinyl Ketimines
J. Org. Chem.  2006, 71,  7110-7112.
166. Salisbury , C. M.; Ellman, J. A.
Rapid Identification of Potent Nonpeptidic Serine Protease Inhibitors
ChemBioChem  2006, 7, 1034-1037.
165. Zhang, Y.; Lewis, J. C.; Bergman, R. G.; Ellman, J. A.; Oldfield, E.
NMR Shifts, Orbitals, and M···H-X Bonding in d8 Square Planar Metal Complexes
Organometallics   2006, 25, 3515-3519.
164. Choe, Y.; Leonetti, F.; Greenbaum, D. C.; Lecaille, F.; Bogyo, M.; Bromme, D.; Ellman, J. A.; Craik, C. S.
Substrate Profiling of Cysteine Proteases Using a Combinatorial Peptide Library Identifies Functionally Unique Specificities
J. Biol. Chem.  2006, 281, 12824-12832.
163. Gosalia D.N.; Denney, W. S.; Salisbury, C. M.; Ellman, J. A.; Diamond, S. L.
Functional Phenotyping of Human Plasma Using a 361-Fluorogenic Substrate Biosensing Microarray
Biotechnol. Bioeng.  2006, 94, 1099-1110.

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