Publications

119. Ahrendt, K. A.; Olsen, J. A.; Wakao, M.; Trias, J. Ellman, J. A.
Identification of Potent and Broad-Spectrum Antibiotics from SAR Studies of a Synthetic Vancomycin Analog
Bioorg. Med. Chem. Lett.  2003, 13, 1683-1686.
118. Cawley, N. X.; Chino, M.; Maldonado, A.; Rodriguez, Y. M.; Loh, Y. P.; Ellman, J. A.
Synthesis and Characterization of the First Potent Inhibitor of Yapsin 1. Implications for the Study of Yapsin-Like Enzymes
J. Biol. Chem.  2003, 278, 5523-5530.
117. Asojo, O. A.; Gulnik. S. V.; Afonina, E.; Yu, B.; Ellman, J. A.; Haque, T. S.; Silva, A. M.
Novel Uncomplexed and Complexed Structures of Plasmepsin II, an Aspartic Protease from Plasmodium falciparum
J. Mol. Biol.  2003, 327, 173-181.
116. Schenkel, L. B.; Ellman, J. A.
Novel Sulfinyl Imine Ligands for Asymmetric Catalysis
Org. Lett.  2003, 5, 545-548.
115. Bednarski, J. J.; Warner, R. E.; Rao, T.; Leonetti, F.; Yung, R.; Richardson, B. C.; Johnson, K. J.; Ellman, J. A. Opipari, A. W.; Glick, G. D.
Attenuation of Autoimmune Disease in Fas-Deficient Mice by Treatment with a Cytotoxic Benzodiazepine
Arthritis & Rheumatism  2003, 48, 757-766.
114. Huang, L.; Brinen, L. S.; Ellman, J. A.
Crystal Structures of Reversible Ketone-Based Inhibitors of the Cysteine Protease Cruzain
Bioorg. Med. Chem.  2003, 11, 21-29.
113. Ellman, J. A.
Applications of tert-Butanesulfinamide in the Asymmetric Synthesis of Amines
Pure Appl. Chem.  2003, 75, 39-46.
112. Owens, T. D.; Souers, A. J.; Ellman, J. A.
The Preparation and Utility of Bis(sulfinyl)imidoamidine Ligands for the Copper-Catalyzed Diels Alder Reaction
J. Org. Chem.  2003, 68, 3-10.
111. Blum, S. A.; Bergman, R. G.; Ellman, J. A.
Enantioselective Oxidation of Di-tert-Butyl Disulfide with a Vanadium Catalyst: Progress toward Mechanism Elucidation
J. Org. Chem.  2003, 68, 150-155.
110. Salisbury, C. M.; Maly, D. J.; Ellman, J. A.
Peptide Microarrays for the Determination of Substrate Specificity
J. Am. Chem. Soc.  2002, 124, 14868-14870.
109. Ellman, J. A.; Owens, T. D.; Tang, T. P.
N-tert-Butanesulfinyl Imines: Versatile Intermediates for the Asymmetric Synthesis of Amines
Acc. Chem. Res.  2002, 35, 984-995.
108. Tang, T. P.; Ellman, J. A.
Asymmetric Synthesis of beta-Amino Acid Derivatives Incorporating a Broad Range of Substitution Patterns by Enolate Additions to tert-Butanesulfinyl Imines
J. Org. Chem.  2002, 67, 7819-7832.
107. Blatt, N. B.; Bednarski, J. J.; Warner, R. E.; Leonetti, F.; Johnson, K. M.; Boitano, A.; Yung, R.; Richardson, B. C.; Johnson, K. J.; Ellman, J. A. Opipari, A. W.; Glick, G. D.
Benzodiazepine-Induced Superoxide Signals B Cell Apoptosis: Mechanistic Insight and Potential Therapeutic Utility
J. Clin. Invest.  2002, 110, 1123-1132.
106. Tan, K. L.; Bergman, R. G.; Ellman, J. A.
Intermolecular Coupling of Alkenes to Heterocycles via Rhodium-Catalyzed C-H Bond Activation
J. Am. Chem. Soc.  2002, 124, 13964-13965.
105. Huang, L.; Ellman, J. A.
General Solid-Phase Procedure to Prepare Novel Cyclic Ketone Inhibitors of the Cysteine Protease Cruzain
Bioorg. Med. Chem. Lett.  2002, 12, 2993-2996.
104. Choi, C. Y. H.; Schneider, E. L.; Kim, J. M.; Gluzman, I. Y.; Goldberg, D. E.; Ellman, J. A.; Marletta, A.
Interference with Heme Binding to Histidine-Rich Protein-2 As an Antimalarial Strategy
Chem. Biol.  2002, 9, 881-889.
103. Chino, M.; Wakao, M.; Ellman, J. A.
Efficient Method to Prepare Hydroxyethylamine-Based Aspartyl Protease Inhibitors with Diverse P1 Side Chains
Tetrahedron  2002, 58, 6305-6310.
102. Brinner, K. M.; Kim, J. M.; Habashita, H.; Gluzman, I. Y.; Goldberg, D. E.; Ellman, J. A.
Novel and Potent Anti-Malarial Agents
Bioorg. Med. Chem.  2002, 10, 3649-3661.
101. Kochi, T.; Tang, T. P.; Ellman, J. A.
Asymmetric Synthesis of syn- and anti-1,3-Amino Alcohols
J. Am. Chem. Soc.  2002, 124, 6518-6519.
100. Wang, X.; Choe, Y.; Craik, C. S.; Ellman, J. A.
Design and Synthesis of Novel Inhibitors of Gelatinase B
Bioorg. Med. Chem. Lett.  2002, 12, 2201-2204.
99. Tan, K. L.; Bergman, R. G.; Ellman, J. A.
Intermediacy of an N-Heterocyclic Carbene in the Catalytic C-H Activation of Benzimidazole
J. Am. Chem. Soc.  2002, 124, 3202-3203.
98. Kehoe, J. W.; Maly, D. J.; Verdugo, D. E.; Armstrong, J. I.; Cook, B. N.; Ouyang, Y.-B.; Moore, K. L.; Ellman, J. A.; Bertozzi, C. R.
Tyrosylprotein Sulfotransferase Inhibitors Generated by Combinatorial Target-Guided ligand Assembly
Bioorg. Med. Chem. Lett  2002, 12, 329-332.
97. Maly, D. J.; Leonetti, F.; Backes, B. J.; Dauber, D. S.; Harris, J. L.; Craik, C. S.; Ellman, J. A.
Expedient Solid-Phase Synthesis of Fluorogenic Protease Substrates Using the 7-Amino-4-Carbamoylmethylcoumarin (ACC) Fluorophore
J. Org. Chem.  2002, 67, 910-915.
96. Maly, D. J.; Huang, L.; Ellman, J. A.
Combinatorial Strategies for Targeting Protein Families.  Application to the Proteases
ChemBioChem  2002, 3, 16-37.
95. Huang, L.; Lee, A.; Ellman, J. A.
Identification of Potent and Selective Mechanism-Based Inhibitors of the Cysteine Protease Cruzain Using Solid-Phase Parallel Synthesis
J. Med. Chem.  2002, 45, 676-684.
94. Dauber, D. S.; Ziermann, R. Parkin, N.; Maly, D. J.; Mahrus, S.; Harris, J. L.; Ellman, J. A.; Petropoulos, C.; Craik, C. S.
Altered Substrate Specificity of Drug-Resistant Human Immunodeficiency Virus Type 1 Protease
J. Virol.  2002, 76, 1359-1368.
93. Lee. A.; Ellman, J. A.
Parallel Solution-Phase Synthesis of Mechanism-Based Cysteine Protease Inhibitors
Org. Lett.  2001, 3, 3707-3709.
92. Tang, T. P.; Volkman, S. K.; Ellman, J. A.
Asymmetric Synthesis of 1,2-Amino Alcohols Using tert-Butanesulfinyl Aldimines and Ketimines
J. Org. Chem.  2001, 66, 8772-8778.
91. Thalji, R.; Ahrendt, K. A.; Bergman, R. G.; Ellman, J. A.
Annulation of Aromatic Imines via Directed C-H Activation with Wilkinson’s Catalyst
J. Am. Chem. Soc.  2001, 123, 9692-9693.
90. Souers, A. J.; Ellman, J. A.
beta-Turn Mimetic Library Synthesis: Scaffolds and Applications
Tetrahedron  2001, 57, 7431-7448.

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