|
260. |
Phelan, J. P.; Patel, E. J.; Ellman, J. A.
Catalytic Enantioselective Addition of Thioacids to Trisubstituted Nitroalkenes
Angew. Chem. Int. Ed. 2014, 53, 11329–11332.
|
|
|
259. |
Xu, J.; Chatterjee, M.; Baguley, T. D.; Brouillette, J.; Kurup, P.; Ghosh, D.; Kanyo, J.; Zhang, Y.; Seyb, K.; Ononenyi, C.; Foscue, E.;Cuny, G. D.; Glicksman, M. A.; Greengard, P.; Lam, T. T.; Tautz, L.; Nairn, A. C.; Ellman, J. A.; Lombroso, P. A.
Inhibitor of the Tyrosine Phosphatase STEP Reverses Cognitive Deficits in a Mouse Model of Alzheimer’s Disease
PLoS Biol. 2014, 12, e1001923.
In search for Alzheimer’s drug, a major STEP forward
|
|
|
258. |
Wangweerawong, A.; Bergman, R. G.; Ellman, J. A.
Asymmetric Synthesis of α-Branched Amines via Rh(III)-Catalyzed C–H Bond Functionalization
J. Am. Chem. Soc. 2014, 136, 8520–8523.
Research Highlight in Nature Chemistry
|
|
|
257. |
Duttwyler, S.; Chen, S.; Lu, C.; Mercado, B. Q.; Bergman, R. G.; Ellman, J. A.
Regio- and Stereoselective 1,2-Dihydropyridine Alkylation/Addition Sequence for the Synthesis of Piperidines with Quaternary Centers
Angew. Chem. Int. Ed. 2014, 53, 3877–3880.
|
|
|
256. |
Buesking, A. W.; Bacauanu, V.; Cai, I.; Ellman, J. A.
Asymmetric Synthesis of Protected α-Amino Boronic Acid Derivatives with an Air- and Moisture-Stable Cu(II) Catalyst
J. Org. Chem. 2014, 79, 3671–3677.
Write-up in Organic Process Research and Development, Research Highlight in Synfacts
|
|
|
255. |
Buesking, A. W.; Ellman, J. A.
Convergent, Asymmetric Synthesis of Vicinal Amino Alcohols via Rh-Catalyzed Addition of α-Amido Trifluoroborates to Carbonyls
Chem. Sci. 2014, 5, 1983-1987.
|
|
|
254. |
Baguley, T. D.; Xu, H.-C.; Chatterjee, M.; Nairn, A. C.; Lombroso, P. J.; Ellman, J. A.
Substrate-Based Fragment Identification for the Development of Selective, Nonpeptidic Inhibitors of Striatal-Enriched Protein Tyrosine Phophatase
J. Med. Chem. 2013, 56, 7636-7650.
|
|
|
253. |
Xu, H. C.; Chowdhury, S.; Ellman, J. A.
Asymmetric Synthesis of Amines Using tert-Butanesulfinamide
Nat. Protoc. 2013, 8, 2271-2280.
|
|
|
252. |
Khan, H. A.; Ellman, J. A.
Asymmetric Synthesis of α-Aminophosphonate Esters by the Addition of Dialkyl Phosphites to tert-Butanesulfinyl Imines
Synthesis 2013, 45, 3147–3150.
|
|
|
251. |
Lian, Y.; Hummel, J. R.; Bergman, R. G.; Ellman, J. A.
Facile Synthesis of Unsymmetrical Acridines and Phenazines by a Rhodium(III)-Catalyzed Amination, Cyclization and Aromatization Cascade
J. Am. Chem. Soc. 2013, 135, 12548-12551.
Research Highlight in Synfacts
|
|
|
250. |
Lian, Y.; Bergman, R. G.; Lavis, L. D.; Ellman, J. A.
Rhodium(III)-Catalyzed Indazole Synthesis by C-H Bond Functionalization and Cyclative Capture
J. Am. Chem. Soc. 2013, 135, 7122-7125.
|
|
|
249. |
Brasse, M.; Cámpora, J.; Begman, R. G.; Ellman, J. A.
Mechanistic Study of the Oxidative Coupling of Styrene with 2-Phenylpyridine Derivatives Catalyzed by Cationic Rhodium(III) via C–H Activation
J. Am. Chem. Soc. 2013, 135, 6427-6430.
|
|
|
248. |
Ischay, M. A.; Takase, M. K.; Bergman, R. G.; Ellman, J. A.
Unstabilized Azomethine Ylides for the Stereoselective synthesis of Substituted Piperidines, Tropanes and Azabicyclo[3.1.0] systems
J. Am. Chem. Soc. 2013, 135, 2478-2481.
Spotlights on Recent JACS Publications
|
|
|
247. |
Duttwyler, S.; Chen, S.; Takase, M. K.; Wiberg, K. B.; Bergman, R. G.; Ellman, J. A.
Proton Donor Acidity Controls Selectivity in Nonaromatic Nitrogen Heterocycle Synthesis
Science 2013, 339, 678-682.
C&E News Research Highlight, Write-up in Organic Process Research & Development, Research Highlight in Synfacts
|
|
|
246. |
Martin, R. M.; Bergman, R. G.; Ellman, J. A.
Synthesis of Isoquinuclidines from Highly Substituted Dihydropyridines via the Diels-Alder Reaction
Org. Lett. 2013, 15, 444-447.
|
|
|
245. |
Lian, Y.; Huber, T.; Hesp, K. D.; Bergman, R. G.; Ellman, J. A.
Rhodium(III)-Catalyzed Alkenyl C-H Bond Functionalization: Convergent Synthesis of Furans and Pyrroles
Angew. Chem. Int. Ed. 2013, 52, 629-633.
|
|
|
244. |
Jung, H. H.; Buesking, A. W.; Ellman, J. A.
Rh-Catalyzed Addition of Arylboroxines to Cyclic N-(Isopropanesulfinyl)ketimines
J. Org. Chem. 2012, 77, 9593-9600.
|
|
|
243. |
Lian, Y.; Bergman, R. G.; Ellman, J. A.
Rhodium(III)-Catalyzed Synthesis of Phthalides by Cascade Addition and Cyclization of Benzimidates with Aldehydes
Chem. Sci. 2012, 3, 3088-3092.
|
|
|
242. |
Verdoes, M.; Edgington, L. E.; Scheeren, F. A.; Leyva, M.; Blum, G.; Weiskopf, K.; Bachmann, M. H.; Ellman, J. A.; Bogyo, M.
A Nonpeptidic Cathepsin S Activity-Based Probe for Noninvasive Optical Imaging of Tumor-Associated Macrophages
Chem. Biol. 2012, 19, 619-628.
|
|
|
241. |
Kimmel, K. L.; Weaver, J. D.; Lee, M.; Ellman, J. A.
Enantio- and Diastereoselective Addition of Cyclohexyl Meldrum’s Acid to β- and α,β-Disubstituted Nitroalkenes via N-Sulfinyl Urea Catalysis
J. Am. Chem. Soc. 2012, 134, 9058-9061.
Research Highlight in Synfacts
|
|
|
240. |
Xue, Y.; Chowdhury, S.; Liu, X.; Akiyama, Y.; Ellman, J. A.; Ha, Y.
Conformational Change in Rhomboid Protease GlpG Induced by Inhibitor Binding to Its S′ Subsites
Biochemistry 2012, 51, 3723-3731.
|
|
|
239. |
Hesp, K. D.; Bergman, R. G.; Ellman, J. A.
Rhodium-Catalyzed Synthesis of Branched Amines by Direct Addition of Benzamides to Imines
Org. Lett. 2012, 14, 2304-2307.
External Link
|
|
|
238. |
Martin, R. M.; Bergman, R. G.; Ellman, J. A.
Synthesis of Pyridines from Ketoximes and Terminal Alkynes via C–H Bond Functionalization
J. Org. Chem. 2012, 77, 2501–2507.
Research Highlight in Synfacts
|
|
|
237. |
Duttwyler, S.; Rheingold, A. L.; Bergman, R. G.; Ellman, J. A.
Highly Diastereoselective Synthesis of Tetrahydropyridines by a C–H Activation–Cyclization–Reduction Cascade
J. Am. Chem. Soc. 2012, 134, 4064-4067.
Research Highlight in Synfacts
|
|
|
236. |
Tauchert, M. E.; Incarvito, C. D.; Rheingold, A. L.; Bergman, R. G.; Ellman, J. A.
Mechanism of the Rhodium(III)-Catalyzed Arylation of Imines via C–H Bond Functionalization: Inhibition by Substrate
J. Am. Chem. Soc. 2012, 134, 1482–1485.
|
|
|
235. |
Kimmel, K. K.; Robak, M. T.; Thomas, S.; Lee, M.
Enantio- and Diastereoselective Addition of Thioacetic Acid to Nitroalkenes via N-Sulfinyl Urea Catalysis
Tetrahedron 2012, 68, 2704-2712.
|
|
|
234. |
Colby, D. A.; Tsai, A. S.; Bergman, R. G.; Ellman, J. A.
Rhodium Catalyzed Chelation-Assisted C–H Bond Functionalization Reactions
Acc. Chem. Res. 2012, 45, 814-825.
|
|
|
233. |
Kimmel, K.L.; Weaver, J.D.; Ellman, J.A.
Enantio- and Diastereoselective Addition of Cyclohexyl Meldrum’s Acid to β- and α,β-Disubstituted Nitroalkenes via N-Sulfinyl Urea Catalysis
Chem. Sci. 2012, 3, 121-125.
|
|
|
232. |
Hesp, K.D.; Bergman, R.G.; Ellman, J.A.
Expedient Synthesis of N-Acyl Anthranilamides and β-Enamine Amides by the Rh(III)-Catalyzed Amidation of Aryl and Vinyl C-H Bonds with Isocyanates
J. Am. Chem. Soc. 2011, 133, 11430–11433.
|
|
|
231. |
Jung, H.H.; Buesking, A.W.; Ellman, J.A.
Highly Functional Group Compatible Rh-Catalyzed Addition of Arylboroxines to Activated N-tert-Butanesulfinyl Ketimines
Org. Lett. 2011, 13, 3912-1915.
|
|
