Publications
| 299. |
Xu, J.; Hartley, B. J.; Kurup, P.; Phillips, A.; Topol, A.; Xu, M.; Ononenyi, C.; Foscue, E.; Ho, S. M.; Baguley, T. D.; Carty, N.; Barros, C. S.; Müller, U.; Gupta, S.; Gochman, P.; Rapoport, J.; Ellman, J. A.; et al. Inhibition of STEP61 Ameliorates Deficits in Mouse and hiPSC-Based Schizophrenia Models Mol. Psychiatry 2018, 23, 271–281. |
|
| 298. |
Tjin, C. C.; Otley, K. D.; Baguley, T. D.; Kurup, P.; Xu, J.; Nairn, A. C.; Lombroso, P. J.; Ellman, J. A. Glutathione-Responsive Selenosulfide Prodrugs as a Platform Strategy for Potent and Selective Mechanism-Based Inhibition of Protein Tyrosine Phosphatases ACS Cent. Sci. 2017, 3, 1322–1328. |
|
| 297. |
Tran, G.; Confair, D.; Hesp, K. D.; Mascitti, V.; Ellman, J. A. C2-Selective Branched Alkylation of Benzimidazoles by Rhodium(I)-Catalyzed C–H Activation J. Org. Chem. 2017, 82, 9243–9252. |
|
| 296. |
Witten, M. R.; Wissler, L.; Snow, M.; Geschwindner, S.; Read, J. A.; Brandon, N. J.; Nairn, A. C.; Lombroso, P. J.; Käck, H.; Ellman, J. A. X-ray Characterization and Structure-Based Optimization of Striatal-Enriched Protein Tyrosine Phosphatase Inhibitors J. Med. Chem. 2017, 60, 9299–9319. |
|
| 295. |
Boerth, J. A.; Ellman, J. A. A Convergent Synthesis of Functionalized Alkenyl Halides via Co(III)-Catalyzed Three-Component C-H Bond Addition Angew. Chem. Int. Ed. 2017, 56, 9976–9980 [Very Important Paper]. |
|
| 294. |
Halskov, K.; Roth, H.; Ellman, J. A. Synthesis of [5,6]-Bicyclic Heterocycles with a Ring-Junction Nitrogen via Rh(III)-Catalyzed C-H Functionalization of Alkenyl Azoles Angew. Chem. Int. Ed. 2017, 56, 9183–9187. |
|
| 293. |
Potter, T. J.; Ellman, J. A. Total Synthesis of (+)-Pancratistatin by the Rh(III)-Catalyzed Addition of a Densely Functionalized Benzamide to a Sugar-Derived Nitroalkene Org. Lett. 2017, 19, 2985–2988. |
|
| 292. |
Tran, G.; Hesp, K. D.; Mascitti, V.; Ellman, J. A. Base-Controlled Completely Selective Linear or Branched Rhodium(I)-Catalyzed C−H ortho-Alkylation of Azines without Preactivation Angew. Chem. Int. Ed. 2017, 56, 5899–5903. |
|
| 291. |
Hummel, J. R.; Boerth, J. A.; Ellman, J. A. Transition-Metal-Catalyzed C–H Bond Addition to Carbonyls, Imines, and Related Polarized π Bonds Chem. Rev. 2017, 117, 9163–9227. |
|
| 290. |
Potter, T. J.; Kamber, D. N.; Mercado, B. Q.; Ellman, J. A. Rh(III)-Catalyzed Aryl and Alkenyl C–H Bond Addition to Diverse Nitroalkenes ACS Catal. 2017, 7, 150–153. |
|
| 289. |
Hummel, J. R.; Ellman, J. A. Convergent Synthesis of α-Branched Amines by Transition-Metal-Catalyzed C−H Bond Additions to Imines Isr. J. Chem. 2017, 57, 916–931 [honoring Bob Bergman's Wolf Prize]. |
|
| 288. |
Wangweerawong, A.; Kolmar. S.; Ellman, J. A. Preparation of (S)-Nonafluorobutanesulfinamide Org. Synth. 2016, 93, 319-330. |
|
| 287. |
Chen, S.; Bacauanu, V.; Knecht, T.; Mercado, B. Q.; Bergman, R. G.; Ellman, J. A. New Regio- and Stereoselective Cascades via Unstabilized Azomethine Ylide Cycloadditions for the Synthesis of Highly Substituted Tropane and Indolizidine Frameworks J. Am. Chem. Soc. 2016, 138, 12664–12670. |
|
| 286. |
Potter, T. J.; Ellman, J. A. Rh(III)-Catalyzed C–H Bond Addition/Amine-Mediated Cyclization of Bis-Michael Acceptors Org. Lett. 2016, 18, 3838–3841. |
|
| 285. |
Jamali, H.; Khan, H. A.; Tjin, C. C.; Ellman, J. A. Cellular Activity of New Small Molecule Protein Arginine Deiminase 3 (PAD3) Inhibitors ACS Med. Chem. Lett. 2016, 7, 847–851. |
|
| 284. |
Weinstein, A. B.; Ellman, J. A. Convergent Synthesis of Diverse Nitrogen Heterocycles via Rh(III)-Catalyzed C–H Conjugate Addition/Cyclization Reactions Org. Lett. 2016, 18, 3294-3297. Research Highlight in Synfacts |
|
| 283. |
Boerth, J. A.; Hummel, J. R.; Ellman, J. A. Highly Stereoselective Cobalt(III)-Catalyzed Three-Component C−H Bond Addition Cascade Angew. Chem. Int. Ed. 2016, 55, 12650-12654 [Hot Paper]. Write-up in Organic Process Research & Development, Research Highlight in Synfacts |
|
| 282. |
Phelan, J. P.; Ellman, J. A. Conjugate Addition–Enantioselective Protonation Reactions Beilstein J. Org. Chem. 2016, 12, 1203–1228. |
|
| 281. |
Mesganaw, T.; Elman, J. A. 4-(Diethylphosphino)-N,N-dimethylaniline e-EROS Encyclopedia of Reagents for Organic Synthesis 2016, , . |
|
| 280. |
Phelan, J. P.; Ellman, J. A. Catalytic Enantioselective Addition of Pyrazol-5-ones to Trisubstituted Nitroalkenes with an N-Sulfinylurea Organocatalyst Adv. Synth. Catal. 2016, 358, 1713–1718. |
|
| 279. |
Wangweerawong, A.; Hummel, J. R.; Bergman, R. G.; Ellman, J. A. Preparation of Enantiomerically Pure Perfluorobutanesulfinamide and Its Application to the Asymmetric Synthesis of α-Amino Acids J. Org. Chem. 2016, 81, 1547–1557. |
|
| 278. |
Boerth, J. A.; Ellman, J. A. Rh(III)-Catalyzed Diastereoselective C–H Bond Addition/Cyclization Cascade of Enone Tethered Aldehydes Chem. Sci. 2016, 7, 1474-1479. |
|
| 277. |
Xu, J.; Kurup, P.; Baguley, T.; Foscue, E.; Ellman J. A.; Nairn, A. C.; Lombroso, P. J. Inhibition of the Tyrosine Phosphatase STEP61 Restores BDNF Expression and Reverses Motor and Cognitive Deficits in Phencyclidine-Treated Mice Cell. Mol. Life Sci. 2016, 73, 1503-1514. |
|
| 276. |
Azkona, G.; Saavedra, A.; Aira, Z.; Aluja, D.; Xifró, X.; Baguley, T.; Alberch, J.; Ellman J. A.; Lombroso, P. J.; Azkue, J. J.; Pérez-Navarro, E. Striatal-Enriched Protein Tyrosine Phosphatase Modulates Nociception: Evidence from Genetic Deletion and Pharmacological Inhibition Pain 2016, 157, 377-86. |
|
| 275. |
Xu, J.; Kurup, P. K.; Azkona, G. M.; Baguley, T. D.; Saavedra, A. C.; Nairn, A. C.; Ellman, J. A.; Perez-Navarro, E.; Lombroso, P. A. Down-Regulation of BDNF in Cell and Animal Models Increases Striatal-Enriched Protein Tyrosine Phosphatase STEP61 Levels J. Neurochem. 2016, 136, 285–294. |
|
| 274. |
Phillips, E. M.; Mesganaw, T.; Patel, A. Duttwyler, S.; Mercado, B. Q.; Houk, K. N.; Ellman, J. A. Synthesis of ent-Ketorfanol via a C–H Alkenylation/ Torquoselective 6π-Electrocyclization Cascade Angew. Chem. Int. Ed. 2015, 54, 12044–12048. Research Highlight in Synfacts |
|
| 273. |
Neitz, R. J.; Bryant, C.; Chen, S.; Gut, J.; Caselli, E. H.; Ponce, S.; Chowdhury, S.; Xu, H.; Arkin, M. R.; Ellman, J. A.; Renslo, A. R. Tetrafluorophenoxymethyl Ketone Cruzain Inhibitors with Improved Pharmacokinetic Properties as Therapeutic Leads for Chagas’ Disease Bioorg. Med. Chem. Lett. 2015, 25, 4834–4837. |
|
| 272. |
Chen, S.; Mercado, B. Q.; Bergman, R. G.; Ellman, J. A. Regio- and Diastereoselective Synthesis of Highly Substituted, Oxygenated Piperidines from Tetrahydropyridines J. Org. Chem. 2015, 80, 6660–6668. |
|
| 271. |
Chen, S.; Bergman, R. G.; Ellman, J. A. Facile Rh(III)-Catalyzed Synthesis of Fluorinated Pyridines Org. Lett. 2015, 17, 2567–2569. |
|
| 270. |
Hummel, J. R.; Ellman, J. A. Cobalt(III)-Catalyzed C–H Bond Amidation with Isocyanates Org. Lett. 2015, 17, 2400–2403. |