Publications
| 282. |
Phelan, J. P.; Ellman, J. A. Conjugate Addition–Enantioselective Protonation Reactions Beilstein J. Org. Chem. 2016, 12, 1203–1228. |
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| 281. |
Mesganaw, T.; Elman, J. A. 4-(Diethylphosphino)-N,N-dimethylaniline e-EROS Encyclopedia of Reagents for Organic Synthesis 2016, , . |
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| 280. |
Phelan, J. P.; Ellman, J. A. Catalytic Enantioselective Addition of Pyrazol-5-ones to Trisubstituted Nitroalkenes with an N-Sulfinylurea Organocatalyst Adv. Synth. Catal. 2016, 358, 1713–1718. |
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| 279. |
Wangweerawong, A.; Hummel, J. R.; Bergman, R. G.; Ellman, J. A. Preparation of Enantiomerically Pure Perfluorobutanesulfinamide and Its Application to the Asymmetric Synthesis of α-Amino Acids J. Org. Chem. 2016, 81, 1547–1557. |
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| 278. |
Boerth, J. A.; Ellman, J. A. Rh(III)-Catalyzed Diastereoselective C–H Bond Addition/Cyclization Cascade of Enone Tethered Aldehydes Chem. Sci. 2016, 7, 1474-1479. |
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| 277. |
Xu, J.; Kurup, P.; Baguley, T.; Foscue, E.; Ellman J. A.; Nairn, A. C.; Lombroso, P. J. Inhibition of the Tyrosine Phosphatase STEP61 Restores BDNF Expression and Reverses Motor and Cognitive Deficits in Phencyclidine-Treated Mice Cell. Mol. Life Sci. 2016, 73, 1503-1514. |
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| 276. |
Azkona, G.; Saavedra, A.; Aira, Z.; Aluja, D.; Xifró, X.; Baguley, T.; Alberch, J.; Ellman J. A.; Lombroso, P. J.; Azkue, J. J.; Pérez-Navarro, E. Striatal-Enriched Protein Tyrosine Phosphatase Modulates Nociception: Evidence from Genetic Deletion and Pharmacological Inhibition Pain 2016, 157, 377-86. |
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| 275. |
Xu, J.; Kurup, P. K.; Azkona, G. M.; Baguley, T. D.; Saavedra, A. C.; Nairn, A. C.; Ellman, J. A.; Perez-Navarro, E.; Lombroso, P. A. Down-Regulation of BDNF in Cell and Animal Models Increases Striatal-Enriched Protein Tyrosine Phosphatase STEP61 Levels J. Neurochem. 2016, 136, 285–294. |
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| 274. |
Phillips, E. M.; Mesganaw, T.; Patel, A. Duttwyler, S.; Mercado, B. Q.; Houk, K. N.; Ellman, J. A. Synthesis of ent-Ketorfanol via a C–H Alkenylation/ Torquoselective 6π-Electrocyclization Cascade Angew. Chem. Int. Ed. 2015, 54, 12044–12048. Research Highlight in Synfacts |
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| 273. |
Neitz, R. J.; Bryant, C.; Chen, S.; Gut, J.; Caselli, E. H.; Ponce, S.; Chowdhury, S.; Xu, H.; Arkin, M. R.; Ellman, J. A.; Renslo, A. R. Tetrafluorophenoxymethyl Ketone Cruzain Inhibitors with Improved Pharmacokinetic Properties as Therapeutic Leads for Chagas’ Disease Bioorg. Med. Chem. Lett. 2015, 25, 4834–4837. |
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| 272. |
Chen, S.; Mercado, B. Q.; Bergman, R. G.; Ellman, J. A. Regio- and Diastereoselective Synthesis of Highly Substituted, Oxygenated Piperidines from Tetrahydropyridines J. Org. Chem. 2015, 80, 6660–6668. |
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| 271. |
Chen, S.; Bergman, R. G.; Ellman, J. A. Facile Rh(III)-Catalyzed Synthesis of Fluorinated Pyridines Org. Lett. 2015, 17, 2567–2569. |
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| 270. |
Hummel, J. R.; Ellman, J. A. Cobalt(III)-Catalyzed C–H Bond Amidation with Isocyanates Org. Lett. 2015, 17, 2400–2403. |
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| 269. |
Oresic Bender, K.; Ofori, L.; van der Linden, W. A.; Mock, E. D.; Datta, G.; Chowdhury, S.; Li, H.; Segal, E.; Lopez, M. S.; Ellman, J. A.; Figdor, C. G.; Bogyo, M.; Verdoes, M. Design of a Highly Selective Quenched Activity-Based Probe and Its Application in Dual Color Imaging Studies of Cathepsin S Activity Localization J. Am. Chem. Soc. 2015, 137, 4771–4777. |
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| 268. |
Jamali, H.; Khan, H. A.; Stringer, J. A.; Chowdhury, S. Ellman, J. A. Identification of Multiple Structurally-Distinct, Nonpeptidic Small Molecule Inhibitors of Protein Arginine Deiminase 3 Using a Substrate-Based Fragment Method J. Am. Chem. Soc. 2015, 137, 3616–3621. |
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| 267. |
Otley, K. D.; Ellman, J. A. An Efficient Method for the Preparation of Styrene Derivatives via Rh(III)-Catalyzed Direct C–H Vinylation Org. Lett. 2015, 17, 1332–1335 [ACS Select Virtual Issue on C-H Functionalization]. |
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| 266. |
Matsushima, Y.; Phillips, E. M.; Bergman, R. G.; Ellman, J. A. Rh(I)-Catalyzed Cycloisomerization of 1,6-Enynes Synlett 2015, 26, 1533–1536. |
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| 265. |
Baguley, T. D.; Nairn, A. C.; Lombroso, P. J.; Ellman, J. A. Synthesis of Benzopentathiepin Analogs and Their Evaluation as Inhibitors of the Phosphatase STEP Bioorg. Med. Chem. Lett. 2015, 25, 1050-1052. |
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| 264. |
Hummel, J. R.; Ellman, J. A. Cobalt(III)-Catalyzed Synthesis of Indazoles and Furans by C–H Bond Functionalization/Addition/Cyclization Cascades J. Am. Chem. Soc. 2015, 137, 490–498. Write-up in Organic Process Research and Development |
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| 263. |
Otley, K. D.; Ellman, J. A. A Lewis Acid-Catalyzed Annulation to 2,1-Benzisoxazoles J. Org. Chem. 2014, 79, 8296–8303. |
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| 262. |
Mesganaw, T.; Ellman, J. A. Convergent Synthesis of Diverse Tetrahydropyridines via Rh(I)-Catalyzed C–H Functionalization Sequences Org. Process Res. Dev. 2014, 18, 1097–1104. |
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| 261. |
Mesganaw, T.; Ellman, J. A. Preparative Synthesis of Highly Substituted Tetrahydropyridines via a Rh(I)-Catalyzed C–H Functionalization Sequence Org. Process Res. Dev. 2014, 18, 1105–1109. |
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| 260. |
Phelan, J. P.; Patel, E. J.; Ellman, J. A. Catalytic Enantioselective Addition of Thioacids to Trisubstituted Nitroalkenes Angew. Chem. Int. Ed. 2014, 53, 11329–11332. |
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| 259. |
Xu, J.; Chatterjee, M.; Baguley, T. D.; Brouillette, J.; Kurup, P.; Ghosh, D.; Kanyo, J.; Zhang, Y.; Seyb, K.; Ononenyi, C.; Foscue, E.;Cuny, G. D.; Glicksman, M. A.; Greengard, P.; Lam, T. T.; Tautz, L.; Nairn, A. C.; Ellman, J. A.; Lombroso, P. A. Inhibitor of the Tyrosine Phosphatase STEP Reverses Cognitive Deficits in a Mouse Model of Alzheimer’s Disease PLoS Biol. 2014, 12, e1001923. In search for Alzheimer’s drug, a major STEP forward |
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| 258. |
Wangweerawong, A.; Bergman, R. G.; Ellman, J. A. Asymmetric Synthesis of α-Branched Amines via Rh(III)-Catalyzed C–H Bond Functionalization J. Am. Chem. Soc. 2014, 136, 8520–8523. Research Highlight in Nature Chemistry |
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| 257. |
Duttwyler, S.; Chen, S.; Lu, C.; Mercado, B. Q.; Bergman, R. G.; Ellman, J. A. Regio- and Stereoselective 1,2-Dihydropyridine Alkylation/Addition Sequence for the Synthesis of Piperidines with Quaternary Centers Angew. Chem. Int. Ed. 2014, 53, 3877–3880. |
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| 256. |
Buesking, A. W.; Bacauanu, V.; Cai, I.; Ellman, J. A. Asymmetric Synthesis of Protected α-Amino Boronic Acid Derivatives with an Air- and Moisture-Stable Cu(II) Catalyst J. Org. Chem. 2014, 79, 3671–3677. Write-up in Organic Process Research and Development, Research Highlight in Synfacts |
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| 255. |
Buesking, A. W.; Ellman, J. A. Convergent, Asymmetric Synthesis of Vicinal Amino Alcohols via Rh-Catalyzed Addition of α-Amido Trifluoroborates to Carbonyls Chem. Sci. 2014, 5, 1983-1987. |
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| 254. |
Baguley, T. D.; Xu, H.-C.; Chatterjee, M.; Nairn, A. C.; Lombroso, P. J.; Ellman, J. A. Substrate-Based Fragment Identification for the Development of Selective, Nonpeptidic Inhibitors of Striatal-Enriched Protein Tyrosine Phophatase J. Med. Chem. 2013, 56, 7636-7650. |
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| 253. |
Xu, H. C.; Chowdhury, S.; Ellman, J. A. Asymmetric Synthesis of Amines Using tert-Butanesulfinamide Nat. Protoc. 2013, 8, 2271-2280. |