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312. |
Maity, S.; Potter, T. J.; Ellman, J. A.
α-Branched Amines by Catalytic 1,1-Addition of C–H Bonds and Aminating Agents to Terminal Alkenes
Nat. Catal. 2019, 2, 756–762.
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311. |
Dongbang, S.; Shen, Z.; Ellman, J. A.
Synthesis of Homoallylic Alcohols with Acyclic Quaternary Centers via CoIII‐Catalyzed Three‐Component C–H Bond Addition to Internally Substituted Dienes and Carbonyls
Angew. Chem. Int. Ed. 2019, 58, 12590–12594 [Hot Paper].
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310. |
Hoang, G. L.; Zoll, A. J.; Ellman, J. A.
Three-Component Coupling of Aldehydes, 2-Aminopyridines, and Diazo Esters via Rhodium(III)-Catalyzed Imidoyl C–H Activation: Synthesis of Pyrido[1,2-a]pyrimidin-4-ones
Org. Lett. 2019, 21, 3886-3890 [cover picture for issue 11, June 7].
Write-up in Organic Process Research and Development
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309. |
Chen, S.; Chan, A. Y.; Walker, M. M.; Ellman, J. A.; Houk, K. N.
π-Facial Selectivities in Hydride Reductions of Hindered Endocyclic Iminium Ions
J. Org. Chem. 2019, 84, 273–281.
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308. |
Dongbang, S.; Pedersen, B.; Ellman, J. A.
Asymmetric Synthesis of (−)-Naltrexone
Chem. Sci. 2019, 10, 535–541 [Editor's Choice].
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307. |
Hoang, G. L.; Streit, A. D.; Ellman, J. A.
Three-Component Coupling of Aldehydes, Aminopyrazoles, and Sulfoxonium Ylides via Rhodium(III)-Catalyzed Imidoyl C–H Activation: Synthesis of Pyrazolo[1,5-a]pyrimidines
J. Org. Chem. 2018, 83, 15347-15360.
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306. |
Chandra Tjin, C.; Wissner, R.; Jamali, H.; Schepartz, A.; Ellman, J. A.
Synthesis and Biological Evaluation of an Indazole-Based Selective Protein Arginine Deiminase 4 (PAD4) Inhibitor
ACS Med. Chem. Lett. 2018, 9, 1013–1018.
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305. |
Boerth, J. A.; Maity, S.; Williams, S. K.; Mercado, B. Q.; Ellman, J. A.
Selective and Synergistic Cobalt(III)-Catalysed Three-Component C–H Bond Addition to Dienes and Aldehydes
Nat. Catal. 2018, 1, 673–679.
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304. |
Hoang, G. L.; Li, Y.; Halskov, K. S.; Ellman, J. A
Synthesis of Azolo[1,3,5]triazines via Rhodium(III)-Catalyzed Annulation of N-Azolo Imines and Dioxazolones
J. Org. Chem. 2018, 83, 9522–9529.
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303. |
Potter, T.J.; Li, Y.; Ward, M. D.; Ellman, J. A.
Rh(III)-Catalyzed Synthesis of Isoquinolones and 2-Pyridones via Annulation of N-Methoxyamides and Nitroalkenes
Eur. J. Org. Chem. 2018, 2018, 4381–4388 [International Adivsory Board 20th Anniversary Issue].
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302. |
Walker, M. M.; Chen, S.; Houk, K.; Ellman, J. A.
Formation of Aminocyclopentadienes from Silyldihydropyridines: Ring Contractions Driven by Anion Stabilization
Angew. Chem. Int. Ed. 2018, 57, 6605–6609.
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301. |
Hoang, G. L.; Ellman, J. A.
Rhodium(III)-Catalyzed C–H Functionalization of C-Alkenyl Azoles with Sulfoxonium Ylides for the Synthesis of Bridgehead N-Fused [5,6]-bicyclic Heterocycles
Tetrahedron 2018, 74, 3318–3324 [Herzon Tetrahedron Young Investigator Award Issue].
MilliporeSigma technology spotlight and commercial availability of ketosulfoxonium ylides
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300. |
Halskov, K. M.; Witten, M. R.; Hoang, G. L.; Mercado, B. Q.; Ellman, J. A.
Rhodium(III)-Catalyzed Imidoyl C−H Activation for Annulations to Azolopyrimidines
Org. Lett. 2018, 20, 2464–2467.
Research Highlight in Synfacts, Sigma/Aldrich technology spotlight and commercial availability of ketosulfoxonium ylides
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299. |
Xu, J.; Hartley, B. J.; Kurup, P.; Phillips, A.; Topol, A.; Xu, M.; Ononenyi, C.; Foscue, E.; Ho, S. M.; Baguley, T. D.; Carty, N.; Barros, C. S.; Müller, U.; Gupta, S.; Gochman, P.; Rapoport, J.; Ellman, J. A.; et al.
Inhibition of STEP61 Ameliorates Deficits in Mouse and hiPSC-Based Schizophrenia Models
Mol. Psychiatry 2018, 23, 271–281.
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298. |
Tjin, C. C.; Otley, K. D.; Baguley, T. D.; Kurup, P.; Xu, J.; Nairn, A. C.; Lombroso, P. J.; Ellman, J. A.
Glutathione-Responsive Selenosulfide Prodrugs as a Platform Strategy for Potent and Selective Mechanism-Based Inhibition of Protein Tyrosine Phosphatases
ACS Cent. Sci. 2017, 3, 1322–1328.
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297. |
Tran, G.; Confair, D.; Hesp, K. D.; Mascitti, V.; Ellman, J. A.
C2-Selective Branched Alkylation of Benzimidazoles by Rhodium(I)-Catalyzed C–H Activation
J. Org. Chem. 2017, 82, 9243–9252.
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296. |
Witten, M. R.; Wissler, L.; Snow, M.; Geschwindner, S.; Read, J. A.; Brandon, N. J.; Nairn, A. C.; Lombroso, P. J.; Käck, H.; Ellman, J. A.
X-ray Characterization and Structure-Based Optimization of Striatal-Enriched Protein Tyrosine Phosphatase Inhibitors
J. Med. Chem. 2017, 60, 9299–9319.
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295. |
Boerth, J. A.; Ellman, J. A.
A Convergent Synthesis of Functionalized Alkenyl Halides via Co(III)-Catalyzed Three-Component C-H Bond Addition
Angew. Chem. Int. Ed. 2017, 56, 9976–9980 [Very Important Paper].
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294. |
Halskov, K.; Roth, H.; Ellman, J. A.
Synthesis of [5,6]-Bicyclic Heterocycles with a Ring-Junction Nitrogen via Rh(III)-Catalyzed C-H Functionalization of Alkenyl Azoles
Angew. Chem. Int. Ed. 2017, 56, 9183–9187.
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293. |
Potter, T. J.; Ellman, J. A.
Total Synthesis of (+)-Pancratistatin by the Rh(III)-Catalyzed Addition of a Densely Functionalized Benzamide to a Sugar-Derived Nitroalkene
Org. Lett. 2017, 19, 2985–2988.
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292. |
Tran, G.; Hesp, K. D.; Mascitti, V.; Ellman, J. A.
Base-Controlled Completely Selective Linear or Branched Rhodium(I)-Catalyzed C−H ortho-Alkylation of Azines without Preactivation
Angew. Chem. Int. Ed. 2017, 56, 5899–5903.
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291. |
Hummel, J. R.; Boerth, J. A.; Ellman, J. A.
Transition-Metal-Catalyzed C–H Bond Addition to Carbonyls, Imines, and Related Polarized π Bonds
Chem. Rev. 2017, 117, 9163–9227.
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290. |
Potter, T. J.; Kamber, D. N.; Mercado, B. Q.; Ellman, J. A.
Rh(III)-Catalyzed Aryl and Alkenyl C–H Bond Addition to Diverse Nitroalkenes
ACS Catal. 2017, 7, 150–153.
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289. |
Hummel, J. R.; Ellman, J. A.
Convergent Synthesis of α-Branched Amines by Transition-Metal-Catalyzed C−H Bond Additions to Imines
Isr. J. Chem. 2017, 57, 916–931 [honoring Bob Bergman's Wolf Prize].
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288. |
Wangweerawong, A.; Kolmar. S.; Ellman, J. A.
Preparation of (S)-Nonafluorobutanesulfinamide
Org. Synth. 2016, 93, 319-330.
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287. |
Chen, S.; Bacauanu, V.; Knecht, T.; Mercado, B. Q.; Bergman, R. G.; Ellman, J. A.
New Regio- and Stereoselective Cascades via Unstabilized Azomethine Ylide Cycloadditions for the Synthesis of Highly Substituted Tropane and Indolizidine Frameworks
J. Am. Chem. Soc. 2016, 138, 12664–12670.
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286. |
Potter, T. J.; Ellman, J. A.
Rh(III)-Catalyzed C–H Bond Addition/Amine-Mediated Cyclization of Bis-Michael Acceptors
Org. Lett. 2016, 18, 3838–3841.
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285. |
Jamali, H.; Khan, H. A.; Tjin, C. C.; Ellman, J. A.
Cellular Activity of New Small Molecule Protein Arginine Deiminase 3 (PAD3) Inhibitors
ACS Med. Chem. Lett. 2016, 7, 847–851.
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284. |
Weinstein, A. B.; Ellman, J. A.
Convergent Synthesis of Diverse Nitrogen Heterocycles via Rh(III)-Catalyzed C–H Conjugate Addition/Cyclization Reactions
Org. Lett. 2016, 18, 3294-3297.
Research Highlight in Synfacts
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283. |
Boerth, J. A.; Hummel, J. R.; Ellman, J. A.
Highly Stereoselective Cobalt(III)-Catalyzed Three-Component C−H Bond Addition Cascade
Angew. Chem. Int. Ed. 2016, 55, 12650-12654 [Hot Paper].
Write-up in Organic Process Research & Development, Research Highlight in Synfacts
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