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320. |
Dongbang, S.; Ellman, Jonathan A.
Synthesis of Nitrile Bearing Acyclic Quaternary Centers via Co(III)‐Catalyzed Sequential C–H Bond Addition to Dienes and N‐Cyanosuccinimide
Angew. Chem. Int. Ed. 2021, 60, 2135-2139.
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319. |
Confair, D. N.; Greenwood, N. S.; Mercado, B. Q.; Ellman, J. A.
Rh(III)-Catalyzed Imidoyl C–H Carbamylation and Cyclization to Bicyclic [1,3,5]Triazinones
Org. Lett. 2020, 22, 8993–8997.
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Gannam, Z. T. K.; Min, K.; Shillingford, S. R.; Zhang, L.; Herrington, J.; Abriola, L.; Gareiss, P. C.; Pantouris, G.; Tzouvelekis, A.; et al.
An allosteric site on MKP5 reveals a strategy for small molecule inhibition
Science Signaling 2020, 13, eaba3043.
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317. |
Walker, M. M.; Koronkiewicz, B.; Chen, S.; Houk, K. N.; Mayer, J. M.; Ellman, J. A.
Highly Diastereoselective Functionalization of Piperidines by Photoredox Catalyzed α-Amino C–H Arylation and Epimerization
J. Am. Chem. Soc. 2020, 142, 8194-8202 [ChemRxiv, 2019: doi.org/10.26434/chemrxiv.11336642.v1].
Research Highlight in Synfacts, Featured in Org. Chem. Highlights: C-N Ring Construction
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316. |
Streit, A. D.; Zoll, A. J.; Hoang, G. L.; Ellman, J. A.
Annulation of Hydrazones and Alkynes via Rhodium(III)-Catalyzed Dual C–H Activation: Synthesis of Pyrrolopyridazines and Azolopyridazines
Org. Lett. 2020, 22, 1217-1221.
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315. |
Shen, Z.; Li, C.; Mercado, B. Q.; Ellman, J. A.
Cobalt(III)-Catalyzed Diastereoselective Three-Component C–H Bond Addition to Butadiene and Activated Ketones
Synthesis 2020, 52, 1239-1246 [Domino C–H functionalization reaction/cascade catalysis in honor of Prof. Mark Lautens].
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314. |
Scamp, R. J.; deRamon, E.; Paulson, E. K.; Miller, S. J.; Ellman, J. A.
Co(III)-Catalyzed C-H Amidation of Dehydroalanine for the Site-Selective Structural Diversification of Thiostrepton
Angew. Chem. Int. Ed. 2020, 59, 890-895.
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313. |
Ellman, J. A.; Ackermann, L.; Shi, B.-F.
The Breadth and Depth of C–H Functionalization
J. Org. Chem. 2019, 84, 12701-12704.
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312. |
Maity, S.; Potter, T. J.; Ellman, J. A.
α-Branched Amines by Catalytic 1,1-Addition of C–H Bonds and Aminating Agents to Terminal Alkenes
Nat. Catal. 2019, 2, 756–762.
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311. |
Dongbang, S.; Shen, Z.; Ellman, J. A.
Synthesis of Homoallylic Alcohols with Acyclic Quaternary Centers via CoIII‐Catalyzed Three‐Component C–H Bond Addition to Internally Substituted Dienes and Carbonyls
Angew. Chem. Int. Ed. 2019, 58, 12590–12594 [Hot Paper].
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310. |
Hoang, G. L.; Zoll, A. J.; Ellman, J. A.
Three-Component Coupling of Aldehydes, 2-Aminopyridines, and Diazo Esters via Rhodium(III)-Catalyzed Imidoyl C–H Activation: Synthesis of Pyrido[1,2-a]pyrimidin-4-ones
Org. Lett. 2019, 21, 3886-3890 [cover picture for issue 11, June 7].
Write-up in Organic Process Research and Development
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Chen, S.; Chan, A. Y.; Walker, M. M.; Ellman, J. A.; Houk, K. N.
π-Facial Selectivities in Hydride Reductions of Hindered Endocyclic Iminium Ions
J. Org. Chem. 2019, 84, 273–281.
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308. |
Dongbang, S.; Pedersen, B.; Ellman, J. A.
Asymmetric Synthesis of (−)-Naltrexone
Chem. Sci. 2019, 10, 535–541 [Editor's Choice].
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307. |
Hoang, G. L.; Streit, A. D.; Ellman, J. A.
Three-Component Coupling of Aldehydes, Aminopyrazoles, and Sulfoxonium Ylides via Rhodium(III)-Catalyzed Imidoyl C–H Activation: Synthesis of Pyrazolo[1,5-a]pyrimidines
J. Org. Chem. 2018, 83, 15347-15360.
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306. |
Chandra Tjin, C.; Wissner, R.; Jamali, H.; Schepartz, A.; Ellman, J. A.
Synthesis and Biological Evaluation of an Indazole-Based Selective Protein Arginine Deiminase 4 (PAD4) Inhibitor
ACS Med. Chem. Lett. 2018, 9, 1013–1018.
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305. |
Boerth, J. A.; Maity, S.; Williams, S. K.; Mercado, B. Q.; Ellman, J. A.
Selective and Synergistic Cobalt(III)-Catalysed Three-Component C–H Bond Addition to Dienes and Aldehydes
Nat. Catal. 2018, 1, 673–679.
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304. |
Hoang, G. L.; Li, Y.; Halskov, K. S.; Ellman, J. A
Synthesis of Azolo[1,3,5]triazines via Rhodium(III)-Catalyzed Annulation of N-Azolo Imines and Dioxazolones
J. Org. Chem. 2018, 83, 9522–9529.
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303. |
Potter, T.J.; Li, Y.; Ward, M. D.; Ellman, J. A.
Rh(III)-Catalyzed Synthesis of Isoquinolones and 2-Pyridones via Annulation of N-Methoxyamides and Nitroalkenes
Eur. J. Org. Chem. 2018, 2018, 4381–4388 [International Adivsory Board 20th Anniversary Issue].
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302. |
Walker, M. M.; Chen, S.; Houk, K.; Ellman, J. A.
Formation of Aminocyclopentadienes from Silyldihydropyridines: Ring Contractions Driven by Anion Stabilization
Angew. Chem. Int. Ed. 2018, 57, 6605–6609.
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301. |
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Rhodium(III)-Catalyzed C–H Functionalization of C-Alkenyl Azoles with Sulfoxonium Ylides for the Synthesis of Bridgehead N-Fused [5,6]-bicyclic Heterocycles
Tetrahedron 2018, 74, 3318–3324 [Herzon Tetrahedron Young Investigator Award Issue].
MilliporeSigma technology spotlight and commercial availability of ketosulfoxonium ylides
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300. |
Halskov, K. M.; Witten, M. R.; Hoang, G. L.; Mercado, B. Q.; Ellman, J. A.
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Inhibition of STEP61 Ameliorates Deficits in Mouse and hiPSC-Based Schizophrenia Models
Mol. Psychiatry 2018, 23, 271–281.
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298. |
Tjin, C. C.; Otley, K. D.; Baguley, T. D.; Kurup, P.; Xu, J.; Nairn, A. C.; Lombroso, P. J.; Ellman, J. A.
Glutathione-Responsive Selenosulfide Prodrugs as a Platform Strategy for Potent and Selective Mechanism-Based Inhibition of Protein Tyrosine Phosphatases
ACS Cent. Sci. 2017, 3, 1322–1328.
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297. |
Tran, G.; Confair, D.; Hesp, K. D.; Mascitti, V.; Ellman, J. A.
C2-Selective Branched Alkylation of Benzimidazoles by Rhodium(I)-Catalyzed C–H Activation
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296. |
Witten, M. R.; Wissler, L.; Snow, M.; Geschwindner, S.; Read, J. A.; Brandon, N. J.; Nairn, A. C.; Lombroso, P. J.; Käck, H.; Ellman, J. A.
X-ray Characterization and Structure-Based Optimization of Striatal-Enriched Protein Tyrosine Phosphatase Inhibitors
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295. |
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294. |
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Synthesis of [5,6]-Bicyclic Heterocycles with a Ring-Junction Nitrogen via Rh(III)-Catalyzed C-H Functionalization of Alkenyl Azoles
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Total Synthesis of (+)-Pancratistatin by the Rh(III)-Catalyzed Addition of a Densely Functionalized Benzamide to a Sugar-Derived Nitroalkene
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Base-Controlled Completely Selective Linear or Branched Rhodium(I)-Catalyzed C−H ortho-Alkylation of Azines without Preactivation
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Transition-Metal-Catalyzed C–H Bond Addition to Carbonyls, Imines, and Related Polarized π Bonds
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