Publications

332. Kaplin, A.; Confair, D. N.; Kim, K.; Barros Álvarez, X.; Rodriguiz, R. M.; Yang, Y.; Kweon, O. S.; Che, T.; McCorvy, J.; Kamber, D. N.; Phelan, J. P. Martins, L. C.;...Wetsel, W. C.; Irwin, J. J.; Skiniotis, G.; Shoichet, B. K.; Roth, B. L.; Ellman, J. A.
Bespoke library docking for 5-HT2A receptor agonists with antidepressant activity
Nature  2022610, online.
331. Greenwood, N. S.; Champlin, A. T.; Ellman, J. A.
Catalytic Enantioselective Sulfur Alkylation of Sulfenamides for the Asymmetric Synthesis of Sulfoximines
J. Am. Chem. Soc.  2022144, ASAP.
330. Gannam, Z. T. K.; Jamali, H.; Kweon, O. S.; Herrington, J.; Papini, C.; Gentzel, E.; Lolis, E.; Bennett, A. M.; Ellman, J. A.; Anderson, K. S.
Defining the Structure-Activity Relationship for a Novel Class of Allosteric MKP5 Inhibitors
Eur. J. Med. Chem.  2022243, 114712.
329. Brandes, D. S.; Ellman, J. A.
C–H bond activation and sequential addition to two different coupling partners: a versatile approach to molecular complexity
Chem. Soc. Rev.  202251, 6738 - 6756.
328. Kazerouni, A. M.; Brandes, D. S.; Davies, C. C.; Cotter, L. F.; Mayer, J. M.; Chen, S.; Ellman, J. A.
Visible Light-Mediated, Highly Diastereoselective Epimerization of Lactams from the Most Accessible to the More Stable Stereoisomer
ACS Catal.  202212, 7798–7803.
327. Xu, C.; Tassone, J. P.; Mercado, B. Q.; Ellman, J. A.
Stereoselective Synthesis of Allenyl Alcohols by Cobalt(III)-Catalyzed Sequential C−H Bond Addition to 1,3-Enynes and Aldehydes
Angew. Chem. Int. Ed.  202261, e202202364 [Hot Paper].
326. Chu, D.; Ellman, J. A.
Three-Component Friedel–Crafts Transformations: Synthesis of Alkyl and Alkenyl Trifluoromethyl Sulfides and Alkenyl Iodides
Org. Lett.  202224, 2921–2925.
325. Brandes, D. S.; Muma, A. D.; Ellman, J. A.
Synthesis of α-Branched Amines by Three- and Four-Component C–H Functionalization Employing a Readily Diversifiable Hydrazone Directing Group
Org. Lett.  202123, 9597–9601.
324. Chen, S.; Chandra Tjin, C.; Gao, X.; Xue, Y.; Jiao, H.; Zhang, R.; Wu, M.; He, Z.; Ellman, J. A.; Ha, Y.
Pharmacological inhibition of PI5P4Kα/β disrupts cell energy metabolism and selectively kills p53-null tumor cells
Proc. Natl. Acad. Sci. USA  2021118, e2002486118.
323. Brandes, D. S.; Sirvent, A.; Mercado, B. Q.; Ellman, J. A.
Three-Component 1,2-Carboamidation of Bridged Bicyclic Alkenes via RhIII-Catalyzed Addition of C–H Bonds and Amidating Reagents
Org. Lett.  202123, 2836–2840.
Write-up in Organic Process Research and Development
322. Dongbang, S.; Confair, D. N.; Ellman, J. A.
Rhodium-Catalyzed C–H Alkenylation/Electrocyclization Cascade Provides Dihydropyridines That Serve as Versatile Intermediates to Diverse Nitrogen Heterocycles
Acc. Chem. Res.  202154, 1766-1778.
321. Shen, Z.; Walker, M. M.; Chen, S.; Parada, G. A.; Chu, D. M.; Dongbang, S.; Mayer, J. M.; Houk, K. N.; Ellman, J. A.
General Light-Mediated, Highly Diastereoselective Piperidine Epimerization: From Most Accessible to Most Stable Stereoisomer
J. Am. Chem. Soc.  2021143, 126–131.
Write-up in Organic Process Research and Development
320. Dongbang, S.; Ellman, Jonathan A.
Synthesis of Nitrile Bearing Acyclic Quaternary Centers via Co(III)‐Catalyzed Sequential C–H Bond Addition to Dienes and N‐Cyanosuccinimide
Angew. Chem. Int. Ed.  202160, 2135-2139.
319. Confair, D. N.; Greenwood, N. S.; Mercado, B. Q.; Ellman, J. A.
Rh(III)-Catalyzed Imidoyl C–H Carbamylation and Cyclization to Bicyclic [1,3,5]Triazinones
Org. Lett.   202022, 8993–8997.
318. Gannam, Z. T. K.; Min, K.; Shillingford, S. R.; Zhang, L.; Herrington, J.; Abriola, L.; Gareiss, P. C.; Pantouris, G.; Tzouvelekis, A.; et al.
An allosteric site on MKP5 reveals a strategy for small molecule inhibition
Science Signaling  202013, eaba3043.
317. Walker, M. M.; Koronkiewicz, B.; Chen, S.; Houk, K. N.; Mayer, J. M.; Ellman, J. A.
Highly Diastereoselective Functionalization of Piperidines by Photoredox Catalyzed α-Amino C–H Arylation and Epimerization
J. Am. Chem. Soc.  2020142, 8194-8202 [ChemRxiv, 2019: doi.org/10.26434/chemrxiv.11336642.v1].
Research Highlight in Synfacts, Featured in Org. Chem. Highlights: C-N Ring Construction
316. Streit, A. D.; Zoll, A. J.; Hoang, G. L.; Ellman, J. A.
Annulation of Hydrazones and Alkynes via Rhodium(III)-Catalyzed Dual C–H Activation: Synthesis of Pyrrolopyridazines and Azolopyridazines
Org. Lett.  202022, 1217-1221.
315. Shen, Z.; Li, C.; Mercado, B. Q.; Ellman, J. A.
Cobalt(III)-Catalyzed Diastereoselective Three-Component C–H Bond Addition to Butadiene and Activated Ketones
Synthesis  202052, 1239-1246 [Domino C–H functionalization reaction/cascade catalysis in honor of Prof. Mark Lautens].
314. Scamp, R. J.; deRamon, E.; Paulson, E. K.; Miller, S. J.; Ellman, J. A.
Co(III)-Catalyzed C-H Amidation of Dehydroalanine for the Site-Selective Structural Diversification of Thiostrepton
Angew. Chem. Int. Ed.  202059, 890-895.
313. Ellman, J. A.; Ackermann, L.; Shi, B.-F.
The Breadth and Depth of C–H Functionalization
J. Org. Chem.  201984, 12701-12704.
312. Maity, S.; Potter, T. J.; Ellman, J. A.
α-Branched Amines by Catalytic 1,1-Addition of C–H Bonds and Aminating Agents to Terminal Alkenes
Nat. Catal.  20192, 756–762.
311. Dongbang, S.; Shen, Z.; Ellman, J. A.
Synthesis of Homoallylic Alcohols with Acyclic Quaternary Centers via CoIII‐Catalyzed Three‐Component C–H Bond Addition to Internally Substituted Dienes and Carbonyls
Angew. Chem. Int. Ed.  201958, 12590–12594 [Hot Paper].
310. Hoang, G. L.; Zoll, A. J.; Ellman, J. A.
Three-Component Coupling of Aldehydes, 2-Aminopyridines, and Diazo Esters via Rhodium(III)-Catalyzed Imidoyl C–H Activation: Synthesis of Pyrido[1,2-a]pyrimidin-4-ones
Org. Lett.  201921, 3886-3890 [cover picture for issue 11, June 7].
Write-up in Organic Process Research and Development
309. Chen, S.; Chan, A. Y.; Walker, M. M.; Ellman, J. A.; Houk, K. N.
π-Facial Selectivities in Hydride Reductions of Hindered Endocyclic Iminium Ions
J. Org. Chem.  201984, 273–281.
308. Dongbang, S.; Pedersen, B.; Ellman, J. A.
Asymmetric Synthesis of (−)-Naltrexone
Chem. Sci.  201910, 535–541 [Editor's Choice].
307. Hoang, G. L.; Streit, A. D.; Ellman, J. A.
Three-Component Coupling of Aldehydes, Aminopyrazoles, and Sulfoxonium Ylides via Rhodium(III)-Catalyzed Imidoyl C–H Activation: Synthesis of Pyrazolo[1,5-a]pyrimidines
J. Org. Chem.  201883, 15347-15360.
MilliporeSigma technology spotlight and commercial availability of ketosulfoxonium ylides
306. Chandra Tjin, C.; Wissner, R.; Jamali, H.; Schepartz, A.; Ellman, J. A.
Synthesis and Biological Evaluation of an Indazole-Based Selective Protein Arginine Deiminase 4 (PAD4) Inhibitor
ACS Med. Chem. Lett.  20189, 1013–1018.
305. Boerth, J. A.; Maity, S.; Williams, S. K.; Mercado, B. Q.; Ellman, J. A.
Selective and Synergistic Cobalt(III)-Catalysed Three-Component C–H Bond Addition to Dienes and Aldehydes
Nat. Catal.  20181, 673–679.
304. Hoang, G. L.; Li, Y.; Halskov, K. S.; Ellman, J. A
Synthesis of Azolo[1,3,5]triazines via Rhodium(III)-Catalyzed Annulation of N-Azolo Imines and Dioxazolones
J. Org. Chem.  201883, 9522–9529.
303. Potter, T.J.; Li, Y.; Ward, M. D.; Ellman, J. A.
Rh(III)-Catalyzed Synthesis of Isoquinolones and 2-Pyridones via Annulation of N-Methoxyamides and Nitroalkenes
Eur. J. Org. Chem.  20182018, 4381–4388 [International Adivsory Board 20th Anniversary Issue].

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