Publications

343. Chu, D.; Zoll, A. J.; Ellman, J. A.
Copper-Catalyzed Three-Component Synthesis of Highly Substituted Morpholines
Org. Lett.  202426, 4803–4807.
342. Greenwood, N. S.; Cerny, N. P.; Deziel, A. P.; Ellman, J. A.
Synthesis of N-Acylsulfenamides from (Hetero)Aryl Iodides and Boronic Acids by One-Pot Sulfur-Arylation and Dealkylation
Angew. Chem. Int. Ed.  202463, e202315701.
341. Vargas-Rivera, M. A.; Liu, A. S.; Ellman, J. A.
Visible-Light-Mediated, Diastereoselective Epimerization of Exocyclic Amines
Org. Lett.  202325, 9197–9201.
340. Greenwood, N. S.; Ellman, J. A.
Sulfur-Arylation of Sulfenamides via Ullmann-Type Coupling with (Hetero)aryl Iodides
Org. Lett.  202325, 4759–4764.
339. Champlin, A. T.; Ellman, J. A.
Preparation of Sulfilimines by Sulfur-Alkylation of N-Acyl Sulfenamides with Alkyl Halides
J. Org. Chem.  202388, 7607–7614.
338. Chu, D.; Ellman, J. A.
Stereospecific Synthesis of Unprotected, α,β-Disubstituted Tryptamines and Phenethylamines from 1,2-Disubstituted Alkenes via a One-Pot Reaction Sequence
Org. Lett.  202325, 3654–3658.
337. Greenwood, N. S.; Ellman, J. A.
Sulfur-Arylation of Sulfenamides via Chan–Lam Coupling with Boronic Acids: Access to High Oxidation State Sulfur Pharmacophores
Org. Lett.  202325, 2830–2834.
336. Liu, J. T.; Brandes, D. S.; Greenwood, N. S.; Ellman, J. A.
Synthesis of N-Acylsulfenamides from Amides and N-Thiosuccinimides
Synthesis  202355, 2353–2360 [Special Issue dedicated to Prof. David A. Evans].
335. Zoll, A. J.; Molas, J. C.; Mercado, B. Q.; Ellman, J. A.
Imine Directed Cp*Rh(III)-Catalyzed N–H Functionalization and Annulation with Amino Amides, Aldehydes, and Diazo Compounds
Angew. Chem. Int. Ed.  202362, e202210822.
334. Tassone, J. P.; Yeo, J. Ellman, J. A.
Three-component carboformylation: α-quaternary aldehyde synthesis via Co(III)-catalysed sequential C–H bond addition to dienes and acetic formic anhydride
Chem. Sci.  202213, 14320–14326.
333. Shen, Z.; Vargas-Rivera, M.; Rigby, E. L.; Chen, S.; Ellman, J. A.
Visible Light-Mediated, Highly Stereoselective Epimerization of Morpholines and Piperazines to the More Stable Isomers
ACS Catal.  202212, 12860–12868.
332. Kaplan, A.; Confair, D. N.; Kim, K.; Barros Álvarez, X.; Rodriguiz, R. M.; Yang, Y.; Kweon, O. S.; Che, T.; McCorvy, J.; Kamber, D. N.; Phelan, J. P. Martins, L. C.;...Wetsel, W. C.; Irwin, J. J.; Skiniotis, G.; Shoichet, B. K.; Roth, B. L.; Ellman, J. A.
Bespoke library docking for 5-HT2A receptor agonists with antidepressant activity
Nature  2022610, 582–591.
331. Greenwood, N. S.; Champlin, A. T.; Ellman, J. A.
Catalytic Enantioselective Sulfur Alkylation of Sulfenamides for the Asymmetric Synthesis of Sulfoximines
J. Am. Chem. Soc.  2022144, 17808–17814.
330. Gannam, Z. T. K.; Jamali, H.; Kweon, O. S.; Herrington, J.; Papini, C.; Gentzel, E.; Lolis, E.; Bennett, A. M.; Ellman, J. A.; Anderson, K. S.
Defining the Structure-Activity Relationship for a Novel Class of Allosteric MKP5 Inhibitors
Eur. J. Med. Chem.  2022243, 114712.
329. Brandes, D. S.; Ellman, J. A.
C–H bond activation and sequential addition to two different coupling partners: a versatile approach to molecular complexity
Chem. Soc. Rev.  202251, 6738 - 6756.
328. Kazerouni, A. M.; Brandes, D. S.; Davies, C. C.; Cotter, L. F.; Mayer, J. M.; Chen, S.; Ellman, J. A.
Visible Light-Mediated, Highly Diastereoselective Epimerization of Lactams from the Most Accessible to the More Stable Stereoisomer
ACS Catal.  202212, 7798–7803.
327. Xu, C.; Tassone, J. P.; Mercado, B. Q.; Ellman, J. A.
Stereoselective Synthesis of Allenyl Alcohols by Cobalt(III)-Catalyzed Sequential C−H Bond Addition to 1,3-Enynes and Aldehydes
Angew. Chem. Int. Ed.  202261, e202202364 [Hot Paper].
326. Chu, D.; Ellman, J. A.
Three-Component Friedel–Crafts Transformations: Synthesis of Alkyl and Alkenyl Trifluoromethyl Sulfides and Alkenyl Iodides
Org. Lett.  202224, 2921–2925.
325. Brandes, D. S.; Muma, A. D.; Ellman, J. A.
Synthesis of α-Branched Amines by Three- and Four-Component C–H Functionalization Employing a Readily Diversifiable Hydrazone Directing Group
Org. Lett.  202123, 9597–9601.
324. Chen, S.; Chandra Tjin, C.; Gao, X.; Xue, Y.; Jiao, H.; Zhang, R.; Wu, M.; He, Z.; Ellman, J. A.; Ha, Y.
Pharmacological inhibition of PI5P4Kα/β disrupts cell energy metabolism and selectively kills p53-null tumor cells
Proc. Natl. Acad. Sci. USA  2021118, e2002486118.
323. Brandes, D. S.; Sirvent, A.; Mercado, B. Q.; Ellman, J. A.
Three-Component 1,2-Carboamidation of Bridged Bicyclic Alkenes via RhIII-Catalyzed Addition of C–H Bonds and Amidating Reagents
Org. Lett.  202123, 2836–2840.
Write-up in Organic Process Research and Development
322. Dongbang, S.; Confair, D. N.; Ellman, J. A.
Rhodium-Catalyzed C–H Alkenylation/Electrocyclization Cascade Provides Dihydropyridines That Serve as Versatile Intermediates to Diverse Nitrogen Heterocycles
Acc. Chem. Res.  202154, 1766-1778.
321. Shen, Z.; Walker, M. M.; Chen, S.; Parada, G. A.; Chu, D. M.; Dongbang, S.; Mayer, J. M.; Houk, K. N.; Ellman, J. A.
General Light-Mediated, Highly Diastereoselective Piperidine Epimerization: From Most Accessible to Most Stable Stereoisomer
J. Am. Chem. Soc.  2021143, 126–131.
Write-up in Organic Process Research and Development
320. Dongbang, S.; Ellman, Jonathan A.
Synthesis of Nitrile Bearing Acyclic Quaternary Centers via Co(III)‐Catalyzed Sequential C–H Bond Addition to Dienes and N‐Cyanosuccinimide
Angew. Chem. Int. Ed.  202160, 2135-2139.
319. Confair, D. N.; Greenwood, N. S.; Mercado, B. Q.; Ellman, J. A.
Rh(III)-Catalyzed Imidoyl C–H Carbamylation and Cyclization to Bicyclic [1,3,5]Triazinones
Org. Lett.   202022, 8993–8997.
318. Gannam, Z. T. K.; Min, K.; Shillingford, S. R.; Zhang, L.; Herrington, J.; Abriola, L.; Gareiss, P. C.; Pantouris, G.; Tzouvelekis, A.; et al.
An allosteric site on MKP5 reveals a strategy for small molecule inhibition
Science Signaling  202013, eaba3043.
317. Walker, M. M.; Koronkiewicz, B.; Chen, S.; Houk, K. N.; Mayer, J. M.; Ellman, J. A.
Highly Diastereoselective Functionalization of Piperidines by Photoredox Catalyzed α-Amino C–H Arylation and Epimerization
J. Am. Chem. Soc.  2020142, 8194-8202 [ChemRxiv, 2019: doi.org/10.26434/chemrxiv.11336642.v1].
Research Highlight in Synfacts, Featured in Org. Chem. Highlights: C-N Ring Construction
316. Streit, A. D.; Zoll, A. J.; Hoang, G. L.; Ellman, J. A.
Annulation of Hydrazones and Alkynes via Rhodium(III)-Catalyzed Dual C–H Activation: Synthesis of Pyrrolopyridazines and Azolopyridazines
Org. Lett.  202022, 1217-1221.
315. Shen, Z.; Li, C.; Mercado, B. Q.; Ellman, J. A.
Cobalt(III)-Catalyzed Diastereoselective Three-Component C–H Bond Addition to Butadiene and Activated Ketones
Synthesis  202052, 1239-1246 [Domino C–H functionalization reaction/cascade catalysis in honor of Prof. Mark Lautens].
314. Scamp, R. J.; deRamon, E.; Paulson, E. K.; Miller, S. J.; Ellman, J. A.
Co(III)-Catalyzed C-H Amidation of Dehydroalanine for the Site-Selective Structural Diversification of Thiostrepton
Angew. Chem. Int. Ed.  202059, 890-895.

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